Multiple testing correction in linear mixed models (MLM) for GWAS

Question

[Denis]

Hi all, I'm performing GWAS with MLM approach. I'm wondering which multiple testing correction method i have to apply to my MLM resulted p-values?

Answer 1

[pfs]

Bonferroni correction

[ATpoint]

Hi pfs,

it would help if you could elaborate on why Bonferroni (over other methods) is the method-of-choice here. This publication might be worth reading.

[h.mon]

This one is also interesting:

A general method for controlling the genome-wide type I error rate in linkage and association mapping experiments in plants

[grant.hovhannisyan]

Just out of curiosity, does the statistical method (MLM in this case) matter on which type of correction to use?