how to find the locations of protein products of a certain list of genes?

Question

[Yingzi Zhang]

Dear all, I need to find locations of protein products of a certain list of genes. For example, TLR1(toll like receptor 1) locates on the cell membrane. Is there any database can realize this goal? I know uniprot subcellular location. But it seems only 400+ genes are in the database. Is there any other database or any method I missed please? Thank you.

Regards, Yingzi

[cpad0112]

sure..try GO terms of CC. CC furnishes cellular component (location) of entity (gene/protein). Use amigo or biomart for extracting GO:CC of entities.

[Doralicia]

Hi, I am doing a similar thing and I also need to filter my protein list by their location. I am trying to figure out how to do it here Get GO terms for location and filter protein table with Rstudio, just got my GO terms but don't know how to filter afterwards. Any ideas? Thanks.

Answer 1

[Pierre Lindenbaum]

convert geneName to uniprot

https://www.uniprot.org/uploadlists/

in the new screen , in the column hearder, click on "columns" , expand "subcellular location" , select "Subcellular location ", save.