Showing more terms in the result of GESA by ClusterProfiler
1
1
Entering edit mode
6.2 years ago
ytlin610 ▴ 70

Hi

I've been working on the gene set enrichment analysis by ClusterProfiler, and I'm able to generate the enriched terms table by the enricher function:

CRE_MapMan_GSEA <-enricher(DEG_cht7_6_up_LocusID$Gene_ID,
                           TERM2GENE=TERM2GENE, 
                           TERM2NAME = TERM2NAME,
                           pvalueCutoff = 0.05)

Result:

  ID               Description                              pvalue

    28.1           DNA.synthesis/chromatin structure        6.96E-19
    31.6.1.1       cell.motility.eukaryotes.basal bodies    4.77E-08
    28.2           cell.motility.eukaryotes.basal bodies    1.63E-06
    24             DNA.repair                               4.38E-06
    31.2           Biodegradation of Xenobiotics            1.32E-05
    27.3.44        cell.division                            1.90E-03
    31.1           RNA.regulation of transcription.         2.24E-03
                   Chromatin Remodeling Factors

However, there're only 7 terms displayed. Does that mean the rest of them are not significant enough? Is there any way I can see the p-values of more terms? I've tried to play with the pvalueCutoff parameter, but the number of the displayed term is still the same.

Thanks!

clusterProfiler R bioconductor • 1.7k views
ADD COMMENT
1
Entering edit mode
6.2 years ago
Guangchuang Yu ★ 2.6k

Try to use different qvalueCutoff value as cut off.

ADD COMMENT
0
Entering edit mode

It worked! Thank you very much!

ADD REPLY

Login before adding your answer.

Traffic: 1915 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6