Tool:BioTuring Browser: Making single-cell sequencing data in published studies really accessible!
3
20
Entering edit mode
6.2 years ago
sonpham ▴ 580

Dear Colleagues,

Today, we are happy to release BioTuring Browser, a modern application for accessing published sequencing data, focusing on single-cell transcriptome. With a web browser, scientists can easily read published papers; with BioTuring Browser, they can actually “read” the underneath sequencing data, and answers many questions that were not revealed in the papers.

In this beta release, BioTuring Browser provides:

  • 3D and 2D PCA/t-SNE visualization of single cells, scaled up to 1.3 million cells on a standard laptop.
  • Batch effect removal
  • Comparison of two conditions (Differentially Expressed Genes and Comparing Cluster Structure)
  • Support automatic and manual cell-type annotations
  • Support real-time cell type prediction
  • Support color mapping for graph-based clustering, k-means clustering, and gene expression.
  • Sub-clustering of a chosen cell population.
  • Marker gene identification
  • A comprehensive knowledge base for gene functions.
  • Access data from new and highly cited single-cell papers in neuroscience
  • Also, the Bulk-RNA seq add-on provides all standard analyses, e.g., PCA, differential expression, gene ontology, pathway enrichment, tissue prediction, etc.

You can download BioTuring Browser at https://bioturing.com/product/bbrowser

Currently, BioTuring Browser is available for MacOS and Windows (beta). We hope to have the Linux version available soon.

Thank you!

Son Pham & BioTuring Team.

Below are some screenshots/videos of BioTuring Browser

3D t-SNE scatter plot

scatter plot

Single cell annotation

Marker gene identification

enter image description here

scRNA-Seq single-cell • 6.9k views
ADD COMMENT
0
Entering edit mode

Great work! Is it commercial?

ADD REPLY
0
Entering edit mode

You can view published data free of charge. For analyzing private data, we charge by each add-on.

ADD REPLY
0
Entering edit mode

Is there a documentation that explicitely explains all relevant steps, such as filtering criteria, data normalization etc?

ADD REPLY
0
Entering edit mode
ADD REPLY
0
Entering edit mode

I've got 2 batches to handle. How to remove the batch effects with this tool? Can you share some instructions?

ADD REPLY
1
Entering edit mode
6.2 years ago
Jennifer Pham ▴ 450

Here's a short video of BioTuring Browser:

ADD COMMENT
1
Entering edit mode
6.1 years ago
Jennifer Pham ▴ 450

Batch effect removal and differential expression analysis are now incorporated in BioTuring Browser:

ADD COMMENT
0
Entering edit mode
5.7 years ago
Jennifer Pham ▴ 450

BBrowser now supports pairing clonotype data with expression data:

ADD COMMENT

Login before adding your answer.

Traffic: 2569 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6