Hi everyone, my name is Samir. I am a postdoctoral researcher at the Icahn School of Medicine of Mount Sinai in New York. We are in the process of deep sequencing HiC and H3K27ac HiChIP libraries. We are trying to figure out the best way to analyze the data for a pilot study. I've noticed that different labs are using different algorithms for HiC/HiChIP analysis. We have currently installed Juicer and HiC Pro. There is no one in our dry lab who specializes in 3D genomics, so we are trying to figure out a streamlined approach to analyze our current datasets and other datasets that I plan to generate. I was wondering if anyone had any advice on this matter.
You may refer this paper
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-015-0678-x