Figure Of Diminishing Sequencing Costs

Question

[Eric Normandeau]

Hi,

There was a question earlier about where to find the famous figure showing the number of sequences publicly available.

I have a similar question. I would like to find a recent figure showing the trend in sequencing cost by base pair, maybe with projections for the next years.

Many thanks!

Eric

[Eric Normandeau]

Thanks everyone for your images and comments :)

Answer 1

[Khader Shameer]

Here is one of my favorite from Forbes magazine

[Alastair Kerr]

I have not see this one, thanks. Added to my side deck for future talks

[Eric Normandeau]

Nice one :) New to me too! Anyone with other versions are also welcomed! (this will help my boss with his presentation :P)

[jvijai]

Someone mentioned at #ASHG2010 that at the rate it is falling, we will start printing money by Sequencing :D

[Rm]

http://scienceblogs.com/digitalbio/2009/04/the_cost_of_dna_sequencing_rev.php

[Rm]

http://www.newscientist.com/article/dn16552-genome-sequencing-falls-to-5000-.html

[Andrea_Bio]

thanks for posing khader

Answer 2

[Brad Chapman]

NHGRI has some nice figures from their large-scale genome sequencing program:

http://www.genome.gov/sequencingcosts/

via Todd Smith on Twitter.

[Eric Normandeau]

Very nice indeed! We seem to have hit a plateau. I will be curious to see the next batch of technologies that will accelerate the decreasing of prices.

Answer 3

[None]

The graph is also given in this presentation here (Slide 5).

[Mary]

Oh, yeah, that's it--thanks for that! Nice to have a slide of that.

Answer 4

[Randy Hall]

Check out Rob Carlson's blog post on "Recent DNA Cost and Productivity Figures from The Economist"

Answer 5

[Mary]

My favorite one that I've seen recently is the one from Lincoln Stein's could paper in Genome Biology recently. It's figure 2 in this reference:

Genome Biol. 2010;11(5):207. Epub 2010 May 5. The case for cloud computing in genome informatics.

I can't show you the figure because I have only an actual paper copy. But he graphs (bp/$) pre- and post- NGS sequencing. It's part of a comparison to the cost of storage. But I still think it's an effective figure, and everyone I have shown it to has gasped.

FWIW.

[Gww]

My favorite part of the figure is that we are quickly approaching the point where it will cost more to store the sequencing information than to sequence it in the first place.

[Chris Miller]

Here's the image, FWIW:

[Mary]

@Chris: thanks--that's nice with the legend. The slide that @none (?) provided is nice to have, but the legend helps too.

Answer 6

[Larry_Parnell]

Check Nature 464:670-671 for a 2-page spread on genomes sequenced, cost/human genome, and numbers of base pairs and reads in data repositories.

http://www.nature.com/news/2010/100331/pdf/464670a.pdf