Question

In silico functional comparison between two strains

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6.1 years ago

112498262 ▴ 10

Can anyone suggest a program that can be ran locally for pairwise functional comparison between strains?

next-gen gene • 1.0k views

ADD COMMENT • link updated 6.1 years ago by n,n ▴ 370 • written 6.1 years ago by 112498262 ▴ 10

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Can you clarify what you mean by functional comparison between genomes/proteomes?

ADD REPLY • link 6.1 years ago by GenoMax 147k

score 0 · Answer 1 · 2018-10-12

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6.1 years ago

n,n ▴ 370

Your question is rather broad, but if you are looking for something general and vast regarding bacterial strains I'd recommend looking into this site: https://www.patricbrc.org/ That platform is really good for bioinformatics starters since it operates fully on a graphic interface; there you can make an account and upload contigs of your strains to annotate them and compare virulence factors, drug targets, proteome, metabolic pathways and many other things. You can even upload raw reads and use the built-in assembler.

Hope this helps.

ADD COMMENT • link 6.1 years ago by n,n ▴ 370

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Thanks very much for your help.

ADD REPLY • link 6.1 years ago by 112498262 ▴ 10