Pathogenicity score ranges

Question

[LimMo]

Hello all,

Could you please help me to know the pathogenicity score ranges for those tools:

• CADD
• MutationTaster
• VEST3
• fathmm

I'm asking because I didn't see their score ranges officially on their websites, so I want to make sure about their scores.

Any help will be appreciated, thanks

Answer 1

[Kevin Blighe]

You should read the publications behind these tools. Then, you will understand the score ranges. Note that some may, technically, have a range that stretches to infinity.