Entering edit mode
6.2 years ago
Bogdan
★
1.4k
Dear all,
please may I ask about your suggestions regarding the packages/methods that I could use for ChIP-seq normalization (shall I compare two ChIP-seq datasets : before_treatment, and after_treatment). thanks a lot !
-- bogdan
Hi Devon, thank you. We do not have input DNA.
Then about the best you can do is 1X normalization of each sample and then either subtract them or take the log2 ratio (
bamCoverage
andbigwigCompare
will do that for you).