Hi All,
Anyone knows is there any paper provided the Heritability (h2) to large number of human phenotypes with twin's data?
or any database to show the h2 for different phenotypes/traits?
Thanks.
Update: done!
@Fabio Marroni give me exactly what I want. Thanks.
Heritability of >2,000 traits & disorders in UK Biobank https://nealelab.github.io/UKBB_ldsc/
If heritability provides such limited information, why do researchers study it? Heritability is of particular interest in understanding traits that are very complex with many contributing factors. Heritability can give initial clues as to the relative influences of “nature” (genetics) and “nurture” (environment) on complex traits, and it can give researchers a place to start teasing apart the factors that influence these traits.
Not twin data, not a database, but I estimated heritability for 43 QTs in humans. This is the link to the paper, where you can find plenty of references to other works estimating heritability for human QTs. I am not aware of any database, but there might be something around.
Great work!! UK biobank don't have the estimation?
Indeed they do, and they have great results! Give a look here!
Can you download the h2 result? I cannot download....
It is SNP-heritability, why they don't have twin based heritability. They have have such data, right?
There are two sets of data:
The file ukbb_all_h2part_results.txt.gz gives an error 415, but I was able to download the file ukbb_all_h2univar_results.txt.gz.
I don't know the difference between the two. You might contact the maintainers regarding the first file.