Biopython for NGS
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6.1 years ago
shuksi1984 ▴ 60

Can I use Biopython to automate the NGS pipeline. If yes, which Biopython library can be used to run GATK, SAMTOOLS, bwa, PICARD. ? I hope my question is clear.

sequencing next-gen SNP • 2.1k views
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For automated pipelines, people use what is known as snakemake

Creating workflows with snakemake and conda

Although, I frequently use shell scripting

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While browsing, I also came across Ruffus. How about Ruffus? Which one would be better sankemake or Ruffus? Although, both are python library but there must be some difference

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I'd suggest snakemake. As far as I know it's more widely used.

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Other options you could explore are NextFlow/FlowCraft

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