Neoantigen prediction Tools

Question

[anu014]

Hello everyone!

Can anyone suggest me some tools for neoantigen prediction in Whole exome sequencing data?

[anu014]

Thanks a lot all! I'll try them and get back to you :)

Answer 1

[Kevin Blighe]

Please refer to the Supplementary Methods of the work by a colleague of mine (from Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade)

Kevin

Answer 2

[Chris Miller]

I've helped to develop pVACtools along with some very talented people from the Griffith lab here at WUSTL. It works well

Vaxrank is another, from the Hammerbacher lab

Answer 3

[fotakisg]

Hello,

You should also check pVACseq (from pVACtools, as mentioned above), MuPeXI and neoepiscope.