Entering edit mode
6.0 years ago
kristjan
▴
170
What program can align a group of unaligned sequences against a large multiple sequence alignment? I need my sequences to have the same alignment length as the reference alignment, but they cannot be combined (like MAFFT -add does).
Do you mean align one or more sequences to a consensus sequence generated using MSA?
I believe CLUSTAL's profile alignment mode can do this (you align new sequences against the existing alignment)