Two dimentional mutation lanscape

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6.0 years ago

rin ▴ 40

Is anyone aware of a way to produce a plot similar to this?

Thank you in advance!

mutations plot visualization • 1.3k views

ADD COMMENT • link updated 6.0 years ago by Ram 44k • written 6.0 years ago by rin ▴ 40

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Looks like a cheap plastic toy from the 1980s. Please provide some context. Where have you seen this, previously?

ADD REPLY • link 6.0 years ago by Kevin Blighe 88k

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Haha I agree, it's not the most good looking one, but it was the only example I found in google.

I saw this one from Alberts' Molecular Biology of the Cell book. I attached the figure I am referring to. In general, I am more interested in this mountains-and-hills visualization of the frequency of discrete data accross the genome.

ADD REPLY • link updated 6.0 years ago by Ram 44k • written 6.0 years ago by rin ▴ 40

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Please use ADD COMMENT or ADD REPLY to answer to previous reactions, as such this thread remains logically structured and easy to follow. I have now moved your reaction but as you can see it's not optimal. Adding an answer should only be used for providing a solution to the question asked.

ADD REPLY • link 6.0 years ago by WouterDeCoster 47k

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It related to Figure 3 from this work from 2007: The Genomic Landscapes of Human Breast and Colorectal Cancers. I checked quickly and could not see anywhere where the authors explained how they generated the figure. Supplementary is HERE.

I mean, it looks like it could have been generated in Matlab, VB, or plotly

ADD REPLY • link 6.0 years ago by Kevin Blighe 88k

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Please provide example data, it should be possible to make 2D scatter plot, and replace "mountains" either with overlapping points with alpha or with size of points based on number of hits on that position.

ADD REPLY • link 6.0 years ago by zx8754 12k

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