Can I use VarScan for tumor_time2/tumor_time1 CNA and SNP calling?

Question

[Pin.Bioinf]

Hello,

I want to compare the CNAs and SNPs in a tumor from same patient in different stages, so I have 3 tumor samples (tims 1, 2 , 3). Can I run varScan to do this or it needs to be just tumor/normal with varScan? Is there a better tool for this?

Thank you a lot.

[Tm]

VarScan for tumor only files