Connection of SNPs to Enzyme activity - database or tool

Question

[ognjen011]

Is there a resource - database or prediction tool - that maps SNPs to changes in enzyme activity? This could either be achieved through prediction of direct effects on structure, or the measurement of products. Either way works fine as long as it elucidates function effects.

Tools like PolyPhen2 do not work as I need effects of SNPs beyond deleterious/neutral status.

Thanks in advance!