Functional annotation chart from DAVID: Analogs or direct affiliations?
0
0
Entering edit mode
5.8 years ago
LRStar ▴ 200

I am trying to determine if genes I am examining are honey bee affiliations or are human analogs. Basically, I:

1) Went to the DAVID bioinformatics software (https://david.ncifcrf.gov/).
2) Used "functional annotation" option.
3) Input a list of BeeBase IDs (all beginning with "GB", such as "GB41545") as a "gene list" with an identifier of “BeeBase_ID”.
4) Selected "functional annotation chart".

One result was KEGG_PATHWAY for Fanconi anemia pathway with 9 genes. So, I clicked on this pathway and, for each of the 9 genes within it, was given the BeeBase_ID, Gene Name, Related gene, and Species. For each of the genes, it does list the Species as Apis Mellifera (honey bee). One example gene is “Fanconi anemia group M protein(LOC409579)”. In NCBI, this gene information can be found at: https://www.ncbi.nlm.nih.gov/gene/409579. There, it also lists the organism as “Apis mellifera”.

Is this gene an insect affliction? Or, is it a human analog but I am simply looking at its related gene for honey bees?

david annotation functional • 1.2k views
ADD COMMENT

Login before adding your answer.

Traffic: 2684 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6