Question

co-expresson network between LncRNA-mRNA

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5.7 years ago

yaghoub.amraei ▴ 10

Hi.all l have four samples from four experiments. 5021 genes that are folding change more than 2 and 2317 long coding RNA. How can I make a co-expression with this data? thanks a lot

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ADD COMMENT • link updated 5.7 years ago by peter.langfelder ▴ 80 • written 5.7 years ago by yaghoub.amraei ▴ 10

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Cross-posted on Bioconductor: https://support.bioconductor.org/p/118906/

ADD REPLY • link 5.7 years ago by Kevin Blighe 88k

score 2 · Accepted Answer · 2019-03-10

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5.7 years ago

peter.langfelder ▴ 80

There's no way to make a meaningful WGCNA with 4 samples (it's not clear what you mean by 4 experiments...).

ADD COMMENT • link 5.7 years ago by peter.langfelder ▴ 80

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Now, how can I get the modules according to correlation?

ADD REPLY • link 5.7 years ago by yaghoub.amraei ▴ 10

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Dude, just don't do it. You cannot create any meaningful results from just 4 samples.

ADD REPLY • link 5.7 years ago by Kevin Blighe 88k