Entering edit mode
5.8 years ago
O.rka
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740
I have a bunch of orthologs for a protein that has a native frame shift from the genomic dna. I’m looking for this protein in another organism. Is it possible to build an hmm from the final product proteins and then identify if it exists within a query dna while considering the frame shift aspect? Maybe if the models can be trained both on dna and protein?