Highly similar bacterial genomes

Question

[karthic]

Hi,

I am searching for some bacterial strains or isolates having very high genome similarity as a model to test a program. Since my knowledge in bacterial genomics is very limited, I would really appreciate if someone suggests the genomes, if possible a paper who have done similar kind of work.

TIA, KK

Answer 1

[Joe]

One of the classic cases would be Mycobacterium tuberculosis and related genomes. Very little recombination if any occurs in mycobacterium and whole genomes can only differ by a few SNPs as far as I know (but I’m no expert on MTB)

[karthic]

Thank you, I will have a look and see if they suit me.