how should i find the correlation between DNA sequence and phenotype across species?

Question

[bangbang3332]

i have a phenotype that i want to investigate, say phenotype A. and i also get a sequence 1. i want to search that if the species get the sequence 1 would obtain phenotype A(or the degree difference), and the species do not have the sequence 1, do not have phenotype A. what is the correlation between sequence 1 and phenotype A?

i want to study the relationship among all mammals.

how should i proceed?

is there any paper that related?

any help would be appreciated!

Thanks a lot !

[Joe]

I’ve changed this from a Tutorial to a question. Tutorials are for posters offering tutorials, not for requesting one.

[Fabio Marroni]

Reading your question it looks like you might be interested in an approach similar to genome wide association mapping. This is a review I found, there are many similar papers.

[bangbang3332]

thank you so much! i would read carefully.