Getting proteins from genomic interval of a genbank file

Question

[fhsantanna]

I am trying to get all proteins from a genbank file considering a sequence interval. Here is the code of the script written in python:

#!/usr/bin/env python

#Script for getting proteins in a range from a genbank file
#Usage: python get_proteins.py file start:end

import sys
from Bio import SeqIO

rec = SeqIO.read(sys.argv[1], 'genbank')
feats = [feat for feat in rec.features if feat.type == "CDS"]
start, end = sys.argv[2].split(':')

desired = set(range(int(start),int(end),1))

for f in feats:
    span = set(range(f.location._start.position, f.location._end.position))
    if span & desired:
        print("%s,%s,%d:%d\n%s\n" % (
                    f.qualifiers['locus_tag'][0],
                    f.qualifiers['product'][0],
                    f.location._start.position,
                    f.location._end.position,
                    f.qualifiers["translation"][0]))

There are two problems: For some regions containing pseudogenes, printing "f.qualifiers["translation"][0]" breaks the script;

$ python get_proteins.py ../gbk/NZ_AOLM01000025.1.gbk 92686:113021 > island_proteins.faa
Traceback (most recent call last):
  File "get_proteins.py", line 24, in <module>
    f.qualifiers["translation"][0]))
KeyError: 'translation'

I know that I must use "try", but I was not successful in doing it.

The second problem is that some genbank files give the following error:

$ python get_proteins.py ../gbk/NZ_CM001555.1.gbk 530979:551299 > island_proteins.faa
Traceback (most recent call last): File "get_proteins.py", line 17, in> <module>
 span = set(range(f.location._start.position, f.location._end.position)) AttributeError: 'CompoundLocation' object
has no attribute '_start'

I did not understand this last problem.

Thank you.

[fhsantanna]

I think I managed the problem:

#!/usr/bin/env python

#Script for getting proteins in a range from a genbank file
#Usage: python get_proteins.py file start:end


#!/usr/bin/env python

#This script is a modification of the script found in Peter Cock's site (http://www2.warwick.ac.uk/fac/sci/moac/people/students/peter_cock/python/genbank2fasta/).
# Usage: python gbk2faa.py  start:end 

import sys
from Bio import GenBank
from Bio import SeqIO

input_handle  = open(sys.argv[1], "r")
output_handle = open(sys.argv[3], "w")

desired_interval = sys.argv[2].split(':')
start = int(desired_interval[0])
end = int(desired_interval[1])
#desired_interval = set(range(int(start),int(end),1))

for seq_record in SeqIO.parse(input_handle, "genbank") :
    print("Dealing with GenBank record %s" % seq_record.id)
    for seq_feature in seq_record[start:end].features :
        try: # Without "try", it crashes when it finds a CDS without translation (pseudogene).
            if seq_feature.type=="CDS" :
                assert len(seq_feature.qualifiers['translation'])==1
                output_handle.write(">%s,%s,%s,%s\n%s\n" % (
                    seq_feature.qualifiers['locus_tag'][0],
                    seq_feature.qualifiers['product'][0],
                    seq_record.id,
                    seq_record.description,
                    seq_feature.qualifiers['translation'][0]))
                pass
        except:
            continue

output_handle.close()
input_handle.close()
print("Done")

Answer 1

[Joe]

I've built something around that exact code before, for this problem: https://github.com/jrjhealey/bioinfo-tools/blob/master/get_spans.py

It requires that the file be a single contiguous genbank (for now). It prints the features, but it should be easy to alter the output to get fasta sequences or similar via Biopython.

Answer 2

[Pierre Lindenbaum]

using xslt and then filter the TSV output with awk

:

wget -O - -q "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=nucleotide&rettype=gb&retmode=xml&id=NZ_AOLM01000025"   | xsltproc --novalid biostar378467.xsl - > out.tsv

view raw README.md hosted with ❤ by GitHub

	<?xml version="1.0" encoding="UTF-8"?>
	<xsl:stylesheet xmlns:xsl="http://www.w3.org/1999/XSL/Transform" version="1.0">
	<xsl:output method="text"/>
	<xsl:template match="/">
	<xsl:text>#locus_tag product from to translation
	</xsl:text>
	<xsl:apply-templates select="GBSet/GBSeq/GBSeq_feature-table/GBFeature[GBFeature_quals/GBQualifier/GBQualifier_name/text()='translation']"/>
	</xsl:template>
	<xsl:template match="GBFeature">
	<xsl:value-of select="GBFeature_quals/GBQualifier[GBQualifier_name/text()='locus_tag']/GBQualifier_value/text()"/>
	<xsl:text> </xsl:text>
	<xsl:value-of select="GBFeature_quals/GBQualifier[GBQualifier_name/text()='product']/GBQualifier_value/text()"/>
	<xsl:text> </xsl:text>
	<xsl:value-of select="GBFeature_intervals/GBInterval/GBInterval_from"/>
	<xsl:text> </xsl:text>
	<xsl:value-of select="GBFeature_intervals/GBInterval/GBInterval_to"/>
	<xsl:text> </xsl:text>
	<xsl:value-of select="GBFeature_quals/GBQualifier[GBQualifier_name/text()='translation']/GBQualifier_value/text()"/>
	<xsl:text>
	</xsl:text>
	</xsl:template>
	</xsl:stylesheet>

view raw biostar378467.xsl hosted with ❤ by GitHub

	#locus_tag	product	from	to	translation
	C441_RS14675	ZIP family metal transporter	1209	400	MTAAEELFVSLAGSDPVMQGLLGGVVIAGMNMLGALLILVWRDPSKRSLDTLLGFAAGVMLAASFTSLILPGIEAAGGNPIPVLAGFVIGVVVLDQADLWIPHVHILVTGKTRADAPETDKKMASVILFIVAITIHNMPEGLAVGVGFGSGDLGTAIPLMLAIGIQNIPEGLAVSIAAVNAGLRNTTYATFAGIRAGLVEIPLAVFGAWAVQYAAALLPYAMGFAAGAMLFVISDEIVPETHSNGHERVATFGTMLGVVVMLYLDVTLG
	C441_RS14680	hypothetical protein	1746	1318	MDVRDAVDTDAEALAAVADAPIRAMRRLIRDRTVRLATAETGSDPHADAPADDEPVLGFVGFDVRDGVLHVTRLGGTETAVRRLLEEPLRFASAEDLPVEVLVLESETPLCDAVEHAGFDRVGHGPRFEGSPTVRYVLDETG
	C441_RS14685	aspartate kinase	1934	3112	MRVVAKFGGTSLGSGDRINRAADSIAAAVEHGHEIAVVASAMGSTTDDLLDEIKFEADDRDRAEIVSMGERTSVRMLKAALAARGVNALFVEPGTDEWPVITNDLGEVDVEATRERAAKLAAELDGVVPVITGFLAQNHDGEITTLGRGGSDTSAVMLGNYMDADEVVIVTDVEGVMTGDPRVVEGARNVGRITVDELRNLSFRGAEVVAPSALSYKDAALDVRVVHYQHGDLLTGGTLIEGEFHNLIDMQEEPLACLTVAGRAIRNRPGILADLSAALREEDINVDSVASGMDSITFYVLEDDSDRAEAVLHDRVIADDALSSVTVEDDIAVVRVTGGELPNRPGVILDIVQPLSDAGINIHDAITSATSVAIFVAWDDREETLGIIQNEF
	C441_RS14690	tryptophanase	3348	4694	MKSYKAKMVEPIELPSREEREAALERAGYNAFNLDARDVYIDLLTDSGTGTMSAEQWAAMIRGDEAYAGSESFARLADSVRDVMGFEHVVPTHQGRGAENVLYGVLLEDGDVVPNNSHFDTTRAHVVNQGAEPVDCPSPASRDPNSTETFKGNFDIDAGYALVEEVGADAIPVVVLTITNNSVAGQPVSMANIRATAEFARDIDAMFVIDACRFAENAHFIKTNEAGYENHSVAEIARAQFEHADAITMSGKKDALVNIGGFAAMRDETVFEHAKQRAILYEGFPTYGGLSGRDIEAMAVGLREAVTPPYVTDRVEQVAELGDLLVEAGVPVYQPTGGHAVYLDAGEVFPHVPKDEYPGQQLVCALYLEGGVRGVELGGFAFPGTDRPDLVRLALPRRTYSREHLEHVAETAAKVMASAGEYGGLEIVEEPPMKELRHFSARLEPVSN
	C441_RS14695	metallophosphoesterase family protein	5384	4725	MRLGVISDVHGNLPALEAVLESMPPVDRLVCAGDVVGYNPWPEECVSELAERDVPTVSGNHDRAVTSGTGFRFNSMAAAGVDYARDALSPASMEWLSALPNTRHVADERVKLAHGHPSDPDRYTYPDDFSPSLLDDEDLLVLGHTHVQGHRIYDDGIVLNPGSVGQPRDGDPRAAYAVADLDAMEIEAERVNYDIDRVAERVREVGLPERLASRLYEGK
	C441_RS14700	IMP cyclohydrolase	6005	5433	MYVGRFVVVGPGIGAYRVSSRSFPNRQVVDRDDALTVGPTPDAPETDNPYIAYNCVREGGDYVVVGNGSQVDPVAEKLDLGYPPRDALAEILLALDYEKDDYDTPRIAGVVGDDEAFIGIVRRDALVVEAVTEPTLVATYEEDDPRAFDLDAETAADAARELYDHEFEHAVCAAAATVGDAVETAFYNGE
	C441_RS14710	KEOPS complex Cgi121-like subunit	6866	6372	MRLVEAEATVANLDSFIAAVGEIADETGATVQAFDARYVVDREHLERATELADRAIARGNEIARDRAVEILLYASGRRQINRAFEIGVSEGTLPVVILVDGGDEAEAEAALFDRLDLEPAETLGDYDEALVRDVFDVGEAELRVADGDLPALVRERVALLAVDR
	C441_RS14715	ATP-dependent DNA helicase	9352	6863	MRTADLTGLPTGIPEALRDEGIEELYPPQAEAVEAGLTDGESLVAAVPTASGKTLVAELAMLSSVARGGKALYIVPLRALASEKKAEFERWEEYGIDVGVSTGNYESDGEWLSSRDIIVATSEKVDSLVRNNAAWMDQLTCVVADEVHLVDDRHRGPTLEVTLAKLRRLNPNLQVVALSATVGNAGVVADWLDAKLVESDWRPIDLKMGVHYGNAVSFADGSQREVPVGRGERQTPALVADALEGDGEGDQGSSLVFVNSRRNAESAARRMAGVTERYLTGDERSDLAELAAEIRDVSDTETSEDLAKAVAKGAAFHHAGLAAEHRTLVEDAFRDRLIKCICATPTLAAGVNTPSRRVVVRDWQRYDGDYGGMKPLDVLEVHQMMGRAGRPGLDPYGEAVLLAKDADARDELFERYIWADPEDVRSKLAAEPALRTHLLATVASGFAHTREGLLEFLDQTLYATQTDDPERLGQVTDRVLDYLEVNGFVEFEGETIRATPVGHTVSRLYLDPMSAAEIIDGLEWAADHRTEKLRALAGETPEKPERDRSDSDDEPGGFQRASEMVADDGGGGAGDDGDGADDTDGGGGDADAFETDRTYPTPLGLYHLVCRTPDMYRLYLKSGDRETYTELCYEREPEFLGRVPSEYEDVAFEDWLSALKTAKLLEDWVGEVDEDRITERYGVGPGDIRGKVETAEWLLGAAERLASELDLDSVYAVREAKKRVEYGVREELLDLAGVRGVGRKRARRLFEAGVESRADLREAEKSRILAALRGRRKTAQNILEAAGRKNPSMDEVDEDDAPDDAVPEDAGFETAKERADQQASLGDFE
	C441_RS14720	ferredoxin	9517	9762	MKVEYDRDTCIGMFQCVDEWEGFEKNVDDGKADLVDAEETDDGVFVREVPEDAEFDAKFAARVCPVEAIRILDDDGEQLVP
	C441_RS14725	hypothetical protein	10014	10859	MFETRTLPSDLESVRDEYAPGALVLDVAGDFDTVPPEAAENLGLVVESLSPAAYPAEWLPDDAPQQLRRYASSDFTIGMPGDGTVTWSRQTTPPVVLVKYRAKGTPDDFLDFLVAEAFVQAGTDEIPEQFLPFFGERYRDLAAATPLGPSETYQVAAALYEGWVGLHTREAFASWEGRYDRLHEAWVDAGGRLDDRLENLPRLVALGRLSFAEATEFACSAVKHERDLPAPFSALDTAAYRDHGPSYAVKWAEKTFEQLAADDDAESGGDADPTADDADSA
	C441_RS14730	hypothetical protein	11459	10881	MDYELAIEDAPETIPGGTGILLLHPSIGETDRIDTDFFKVDTDHFLVISTRTTAREVEQKLEHYEVDESSATILDTLSIERGYSRRSSDNIHYVASPDDLDAIVEKTRQFLEGHDGKLRLSVDSVTEMAYYADEDGAFEATKQILELLDEFDAVGLFHLSKEVHDQETLDRFRELFDGVVDLNEDGTVTTEF
	C441_RS14735	DUF2391 family protein	12011	11553	MVGVRRRFALADTAQQVVGGFLLAGPFVVTEEVWVLARSMSFAQALLTLCIVLAVGYGALYKADDRDPDREREVGGIPVRFISLISVSYLSVFILALAFDAPGTFLSDVSGQSLVTVLGYEVDLAVLRITLKATSVGAVFSVIGAATADSLF
	C441_RS14740	class I SAM-dependent methyltransferase	12138	12818	MSVRDEFDAWAADGRDKGMEDRHWHTAKHALARMPVEEGDTVVDLGTGSGYALRALRDTKGIGRGFGLDGSPEMVQNARAYTDTDDLSFLVGDFDDLPFEDDSVDHVWSMEAFYYAADPHHTLEEVARVLRPGGTFYCAVNYYEENVHSHEWQDLISIDMTRWSHAEYREAFRDAGLHVAEQDSIADLDIDIPAAAEFPTDDWETREAMVERYRTFGTLLTVGVAP
	C441_RS14745	ABC transporter ATP-binding protein	13985	12849	MRLELDAVSKRYGSATALDSVSLSVDDGEFFTLVGPSGCGKTTTLRCIAGFEAPTEGAVRFDGESMAGVAPESRGVGVVFQNYALFPHLSVGENVAYGLRFTDPPGGGSRDDRVAELLDLVDLAGFEDRDPDSLSGGQQQRVALARALAPGPDLLLLDEPMSALDARLRDRLRRQVKHIQSELGVTTVYVTHDQSEALAVSDRVAVLNRGRVEQVGDPRELYHRPRTRFVAEFLGENNVLDAVVESRPETGGIRVGVGDAVFTLAEGRRVLGRAGAVSGERAENDAKDGSRPARPEPGDELTFCVRPEQLRVGAGTNQIRGTVVDTEFQGATTRVRLDWGETELVVAVDDGGEQSDAGFEIGTTMEVGFDPAAAHIVE
	C441_RS14750	iron ABC transporter permease	15822	14101	MSRVSASVRRAARALEQRLLTLVAALTAVVLLVLFYYPVATVFADAVLADGRLTVEPIAAVLTSEFYLVDIIWFTAKQAFYSTLASLALGLPAAWLFARFEFRGRETLRSLTILPFVMPSIMVAIGFVATFGRNGTLNRALSLVGLPPVELLFTLEAIIVAHAFYNAPLVARVVTAAWESVDARTVETARSLGAGPRRAFRDVVLPQLLPSIGVGATLTFIFTFASFPIVLALGGFQLATIEVFVYSRVRDLAYAEAASLAVVETAVSITLTAVYLRYEASQRSAGGAANPLPRRSVLPSDWTPKSTLRTVGIAGYALVVGLVFVVPIASMVLASVTGGDGGFTLANYAFLAERQATGASFQVKPLPAILNSLGFAAGTLVVAVPMGVTMAVLTTRRYRGRGLIDVLSMAPFAVSGIVVGLGLLRGLVFGVDVLGTRIRVTGALAIVAAHAVGAYPFVTRNVAPLFARLDGRLVESARSLGATRTRALVDIELPLVWTGVVAGAAFAVAISIGEFDSTIILAEGAGSYTMPVAVERFLGRRLGPATAMGCLLLLVTSASFLVVDRFGGRWGEL
	C441_RS14755	thiamine ABC transporter substrate-binding protein	16974	15832	MRRRSFLKAAGAGGVSALLAGCAGTGGDEATTEASGDATETTTTTQGTTTGGESPTLTVGTYGSFVDAPSSSPGPWLKEAFESEFDATLEWQTPDSGVNYYIERALRGVESGADLYVGLDAQMLVRIDENLDDALFSPAEGLSRLGDVNEQLNFDPQGRAVPYDTGYISLVYDETYGDGDGDFVAPETFDGLLESEYAGALLAQNPTSSATGQAFLLHTIDAKGEDGYLDYWASLKENDVRVLGNWEDSYNAYSNGEAPMVVSYSTDQVYAAESGEDMARHQIRFLNDEGYANPEGMAPFADASNPDLAAEFMDFVLRPEVQAEIAVRNVQFPATTTAELPEEFAQYAQEPPEAVTFSYDRLQNNLSDWTDAWAREFASK
	C441_RS14760	AI-2E family transporter	17103	18185	MTASRPYVFGGVLALFALLAAVMLANVLATVFFAITVAYLLVPLRRGLEARGASRWVASLAATVVAAVGVVVVLAPLFVILFLRLSDILELAALLPDVVTVEFLGMVETVTLDDVVAVGLGLLQSVGRAAATAAPVVLIKLTLFGFLVFALLLSGDAVGRTLLALVPADYRDAATALNERARETLFAIYVLQAATAVGTFAIGLVVFWALGYDYVVTLATVAAVLQFIPIVGPSVLLAAMAAYHVAVGDLVAAALVVAVGGFAVAWLPDILIRPRLAKETADLPGSLYFVGFVGGLLSLGPVGIIAGPLVVALLVESVDLLGAELRVDGGGGVGGGGDDGDESDGTAGTEGGDAADSLQS
	C441_RS14765	sulfurtransferase	18971	18195	MVDVVSSDWLADRLGDVRVVDVRDGWEFDGIGHLPGAVSIPFDSFRSADGDVGMLPGRDAWTDLLSGAGIAADDDVVAYDDTHGVFAARFLVTALLYGHDPDRLHLLDGDFSAWNRERETTTEATEVAETVYEITEPAETPLVDFEAVEAALDDPETVTVDTRDPAEYEEGHLPGAVNVDWRELVDDETRGLKPRDELDSILEAAGVTPDRRVVLYCNTARRISHTYVVLSHLGYDDVAFYEGSLTEWEARDGAVVED
	C441_RS14770	sulfurtransferase	19223	20083	MSNSDYAKDVLVSADWVESHLDEFQSDDAAYRLVEVDVDTEAYDESHAPGAIGFNWESQLQDQTTRDVLTKEDFEDLLGSHGISEDSTVVLYGDNSNWFAAYTYWQFKYYGHEDVHLMNGGRDYWVDNDYPTTDEVPSFPERDYTAKGPFEDIRAYRDDVEKAVDKGLPLVDVRSPEEFSGEILAPPGLQETAQRGGHIPGASNISWAATVNDDGTFKSADELRDLYADQGIEGDESTIAYCRIGERSSIAWFALHELLGYENVTNYDGSWTEWGNLVGAPVEKGN
	C441_RS14775	short-chain fatty acid transporter	21579	20137	MTNAIRQAAERSSKLVEQYLPDAFLFAIILTGVAFVLALVSVAPGEGTGVVGHAGNLLLDGWYGGFWNLLSFGMQMTLILMTGYALAQTKPVDWLLTRLARVPNTERGAAAMVPVVAAAASFVHWGLGLVVGALFARKIATEMRGIDFPIVVAGAYSGFVVWHGGLAGSIPLLLNTEDNFLIEAGILDTTFGTGGTIFTVANLALVVAVGFLFLPALFALMYPTDETKKTPIDPAEFEAATDGGEQTTSGWASTAVPEDASLATRIEHSLGIGVAIGLVGLLAVALYFFEGVQNGTMPWNNLNLNIVNFGFLFLGLLFHGTPKAYIEAIVEAVENVWGIILQFPFYAGIMGIMAYAPEGSVSLATQIAQGMVAVAPDGTLPAFAFFTAGLVNFFVPSGGGEWAVIGETLVTAAKASGESIPRVAVAASWGDAWTNMIQPFWAIPLLSISGLSVRDIMGYCVMVLLGAGVLVAVGISVLPM
	C441_RS14780	hypothetical protein	21766	22365	MTELLDTLRDDHETPLSRLGSSKALYAVTGGEMDGDAVRAAAAAEAAAAADLFDWWADDEPNDEAAALFSDLADTARDHADTVDAEPDGSKPNVYDVLAEFETTDGRLGGALARALVSLKTVEQMVGFFVGDADPMAANDFRTLKSDLNDQLDALGAAVSDLVEDDAVAREAADAVVEAAYDEYVETLEGMGVKPKNVC
	C441_RS14785	hypothetical protein	22772	22503	MTRAELERASNLLKEAAEATDGDVQERLYEQSDQLAKLATREQGPDHGRLARHMTVLHDLAEDLDGDVAETVREARSEVLEYRKGVPGV
	C441_RS14790	excinuclease ABC subunit UvrB	22861	24963	MSESGPLSADRPDADREFRVDAPFDPAGDQPEAIEALARGFREGADVQTLLGVTGSGKTNTVSWVVEEIQKPTLVLAHNKTLAAQLYEEFKGLFPDNAVEYFVSYYDYYQPEAYIEQTDTYIDKDMSINEEIDRLRHSATRSLLTRDDVIVVASVSAIYGLGDPKNYTDLSLRLEVGQGMDRDELLGALVDLNYERNDVDFRQGTFRVRGDTVEVFPMYGRYAVRIEFWGDEIDRMLKLDPLAGEVKSSEPAVLVHPAEHYSIPEAQLEGAISEIEELMEQRVKHFQRQGDLVAAQRIEERTTFDIEMLRETGHCSGIENYSVHLSDREPGDAPYTLLDYFPDDFLTVIDESHVTLPQIKGQYAGDKSRKDSLVENGFRLPTAYDNRPLTFEEFEETVGQALFVSATPGDYEREHSDQIVEQIVRPTHLVDPRVEVTEATGQVDDLMARIDERVDRDERVLVTTLTKRMAEDLTEYLEEAGVDVAYMHDETDTLERHELIRSLRLGDIDVLVGINLLREGLDIPEVSLVAILDADQQGFLRSETTLVQTMGRAARNVNGEVVLYADEMTDAMEAAISETQRRRRIQQAFNEEHGYTPTTIEKEVGETNLPGSKTDTRGVSGDEPADADEAVEQIAFLEDRMQEAADNLEFELAADIRDRIQTLRREFDVDALEDGVAPEYPDEHDGDGDGDGGLAPPDEF
	C441_RS14795	NUDIX hydrolase	24970	25389	MSRPPTLTFAAGGLLRRDDGRLCLVHRPRYGDWSLPKGKLEPGETLVETAVREVREETRCAVDCGGFAGRYEYRVPDDAGTRSGPKGVFVWHMRVAAEHPFEPGGEVDARRWVTPAEALDRLTYETERALVRRAFELNE
	C441_RS19135	hypothetical protein	25589	25783	MVRGFEHSVLDSSGDHRTPVHPVCDAVASSGDGEHARVGAAGDSANGLFSTRHSTRVHADATAY
	C441_RS14800	sulfite exporter TauE/SafE family protein	25798	26880	MSSQSLSHVQKSFLKYQHILVFIAPLLFLASVLTMAPTPSGAGMEYWLQYWWLFPVFLTGATIVNTVGISGSALFVPFLIFIFPIFAHPLDSSTLVKVGLISEAFGLSSSAVAFIQYGLVDRRLALTLVGGSIPFVVGGALLSFVIPDVVFHALLGIALLAASYLLFTADLGHEDHGSSGSDHAAATDGGVSASLPNDPGKLGPAGVNTADDGTVTRVDREGDDYTYTRGGYLRRFANYSVGGMFQGLAGFGIGELGIISMLGTKVPVRVAIGTNHIVVALTAILASLVHVFGGGLVGGHSLSLATTPWNMVVFTVPATVLGGQIAPYVSNALETSVIKNFVGVLFAVISVALFLMALGI
	C441_RS14805	universal stress protein	26949	27389	MYDHILLPTDGSDATDATIEHAATLAETYGATVHVLSVADSRNRFESPSAGIAPDVWEKSELERAESAADAAIEALPDGVETERTVVEGVPHSTIVDYAADGDIDLVVMATHGRTGLDHYLVGSVTERVVRQSDAPVLTVRAADEE
	C441_RS14810	acyl-CoA thioesterase	27903	27409	MQQQSSVGTRSLSASRAEMSEILMPNDTNNLGRALGGRILEWMDVCGAIAGRRFAERQVVTASMDHVDFLAPIDVGDVVTVEAYVFDTGRTSMDIKVDVTAERPSEGDRRETLTSFFTFVALDDDEKPVPVPDLVCDSQEERELRDSALQKRREHRAALAEEFE
	C441_RS14815	hypothetical protein	28053	28328	MSARTADRWWDADTRLSSAFGGTFPKVPTLVRPDGWGISRDPNSTHRAVSRLTSASRLAEPRRPDDGTHVGRPRRPATTLYRPRCAERVTD
	C441_RS14820	SPFH/Band 7/PHB domain protein	29552	28350	MDSLFYQLGKLSASSSSSSSGAARVDSEPGRIPRWLGPLAVAVVVFGLAVVVFPVTPLTLAGYVALALAVAAVYDAVEIVQAYEKRTLTVFGDYKGILEPGLNVVPPFVSKTYRFDMRTQTLDVPSQEAITEDNSPVTADAVVYIRVMDPERAFLQVDNYRRAVSLLAQTTLRAALGDMELDDTLARRDHINARIRRELDEPTDEWGVRVESVEVREVKPSKDVENAMEQQTSAERRRRAMILEAQGKRRSAVEKAQGDKQSNIIRAQGEKQSQILEAQGDAISTVLRARAAESMGERAIIDKGMETLANIGTSPSTTYVLPQELTSLLGRYGKGLSGSDIQQAAGLESKAFDEETRELLGLDDISEILGELDGIETADISADAVDIEIEDGGVETERVE
	C441_RS14825	hypothetical protein	29645	29839	MRTNRGRIDVEDLLKIILLLVLVWLVLEIIGEVLGLFGALLGPLQPLLGLVVAALIVLWLLDRI
	C441_RS14830	2'-5' RNA ligase family protein	29895	30392	MYSLNVPVPGRVARLASDLFPYLASFDRVRDRHTLVCKRFEDDDLDRLREQLRHALAGQPAFEARVTDIRFFEDPPRGAAPVVYLAVESPGLLDLHRALADEFGAIEGIEGDDYVPHVTLARGGSVADARAVASQPLDPIEWTVSQLDVYDSSFRETAASISLPA
	C441_RS14835	cytochrome P450	31820	30444	MSSTPPGPKGLPLFGASRQYARDPFTFLTAVADAYGDVVHFDLGPLDTYMLTNPADVETVLVSEASKFRKPQFQDRAIGDLLGDGLLMSEGATWKKQRRLAQPAFDVRRISTMAGMMTDRTASMLSSWGDGDVVDVQLEMARLTVEIIVDAMFGTDLDDERVRRVQENLEPLGARFEPDPLRFLTPDWAPTRENRQYKEALSELESLVWDIVEERRGTEYGETPASSVSAGATGEEGPMDLLSILLRAYDEGEQTEKNLRDELMTMLLAGHDTTALTLTYAWYLLSQHPEAEAKLHRELDEVLDGRTPTFEDVRELEYTERVLNEAMRLYPPVYVMFREPKVDVRLGGYRVPAGSAIMLPQWVVHRSDRWWDDPLSFDPDRWAPERTGDRPRFAYFPFGGGPRHCIGKHLSLLEGRLILGTVAQRYELDYVRDEPFSLRGSLTMHPEEPMGMRLRARD
	C441_RS14840	ATP-dependent DNA helicase	34103	31899	MAHANGAPDDGDADGAWRFFPYDEPYPNQEAAMAGIADALDDERNVLLEGATGTGKTISALVPALSYAREHDKTVVITTNVHQQMRQFVEDARAITREEAIRAVVFRGKSSMCHIDVGFQECQTLRDTTRSIVEKESDKAELSEQAQSLLDGMREGESGAADARSAVTDELDALDDELEELKEGNYCEHYYNNLTRNTDQFFQWLFDDVRTPDEIFEYAGKQNLCGYELLKEGMEGIDLVVCNYHHLLDPMIREQFFRWLDRDPDDVITVFDEAHNIESAARDHASRALTENTLESAMNELEDEDDSRAESARNVIGTFLDALRDSYEEAFGFGEREQVGENWYDLSIANQGRRDDLTMEFLQSYEGRGIDVEVELALQLGKQLDEQYEDAYKNGEATTRKECQTLQAANFIADWTEMGGELGRHPMLSVRRDGGTDEIYGRAELYTCIPREVTRELFEEVHASVLMSATLRPFDVTEGTLGLENPVTMAYGLEYPEENRRTFSVSLPALFSSERDDPGTQETIEEMLADAAAFTPGNTLVFFPSYAEAERHHERLRTNPDVDAELFLDEPGVRAEELRREFVGKDGAVLLTSLWGTLAEGVSFDGDDARTVVVVGVPYPHLSERLEAVQAAYDRAYRGKRDAGWRYAVEIPTIRKTRQALGRVIRAPDDFGVRVLADKRYTRESSSMGKYGVRGSFPVEERAEMVDIAPNKLKFAMLNFYADRDAYDGDPPRP
	C441_RS14845	ester cyclase	34254	34718	MDPIPTAEMKATVRHVEEAVWNGRDPAAFDELATDDFVMHDPMGDRGVDGAREMVQAVLDGTPDLEFTVDDLFAAGDRVAVRYTLEGTNEAPSYLTAEPTGNHWQSSGITIYRFEGDRIAEQWDAFDYFGTMRQLGLIPSEAETDAEGSAGAPA
	C441_RS14850	ornithine carbamoyltransferase	35631	34732	MLETTHFTDIDDISASELDRVLTHAADIKSGDDETQLTRATLAMLFEKPSTRTRVSFETGMTELGGHALFLGPEDIQLGHGEPLSDTARVLGRYGDAIMARLFEHEDLLEIAEHSDVPVINGLTDDAHPCQTLADLLTIREHVGDFDEVSAAWVGDGNNVGQSFVLGCAMAGIDLTVATPPAYGVDDDVLEKADELGSAPTITTDPEEAVSDADVVYTDVWISMGQEDQRHEKLQAFEGFQLNEELLSGTDAKVMHCLPAHRGEEITGDVLEGERSLVWDQAENRLHAQKGLIVELLEE
	C441_RS14855	[LysW]-lysine hydrolase	36843	35701	MNAEIEREDDEADVENAGAADAETDASAVSDDGTDALDEGEWAEARHLLYDMVSTPSVSGEEEAAAEVLKAFFEAHDREVWIDEIGNVRAPADDAVLLTSHIDTVPGDVPVKIEDGVLWGRGSVDATGPLCSMAAAAVETGVSFVGVVGEETSSRGAWHLVEDREEPDAVVNGEPSGWDGVTLGYRGFLSGTYISTSELGHSSRPEENAIQSAVAWWSRVADFFDEERDGVFDTVTTKPVRFDGGPSDDGLAVEATVDVQFRVPPRYTIDDVREVAESELTRGGVHWNKPIPPVMMSPRTDVARAFRVAIRNVGGVKPRLLRKTGTSDMNIFAGTWDCPMATYGPGDSDLDHAPNEHLDLAEFDSAIDVLVDVCERLADD
	C441_RS14860	acetylornithine/succinylornithine family transaminase	37976	36840	MSGFVFNEKPIAIESGEGPYLYSGDGTEYLDFGASYAVAALGHSHPAVTSAIQEQAAKLTYVQASYPVEVRTELYEKLATLAPGDISNVWLCNSGTEANEAAMKFARSATGREKIVATKRAFHGRTLGSLALTWKQKYKKPYEPVAGGVEFVSYGDEAELAEAVDDETAAVFLEPIQGEGGINPATAEYLQTARDLTEDAGAALVFDEIQTGIGRTGSLWACENAGVVPDILTSAKGIANGLPLGATLCADWIADGAASHGSTFSGGPVVCAAANATLDTIVEEDLPGHAAAVGDYLTTELEAAVEEHDLPVREVRGDGLMVGVEVKRGANRTLKHLALSEQLLALPAGRTVVRFLPPLVIEEEHADRAVDAMTNVLS
	C441_RS14865	acetylglutamate/acetylaminoadipate kinase	38905	37973	MTGYTREELLAAHEQLVDNEANLLTDGGKEPPVVVKIGGAKAVDPKGAVSDVAHLVANGTDVVVVHGGSTAVDETLEELGEEPTYVESPSGVSGRFTDERTMEVFSMVMPGKLNTDLTALFREAGVDALGLSGVDGGLLTGPRKSAVRVVEDGKKKIKRGDHSGKITSVNATLLETLLDGGYTPIVTVPMLADDGVPVNADADRAAAAVAGALGAKLVVLTDVKGVYADPDDESTLIETADTPEGFSALESAAEGFMTKKVMAAKEALDGGAAEVVVSDANLNDPIVTALNGGGTHVTPGALVEAEGAEQ
	C441_RS14870	N-acetyl-gamma-glutamyl-phosphate reductase	40006	38963	MSDRLTAGVVGGSGFTGGELLRLLDGHPNFDVEQATSRSYERKTVGHVHPNLRHLDLRFTSPEDLESVDVLFTATPHGVSMEHIDAFQDAADTVVDLSADFRLSEAAQYDEWYDGHVCPEYLEQSEYALPELNRENLPGADLIAAGGCNATATILGLKPLFDAGILSGDEQVVVDVKVGSSEGGAGASKASSHAERSGIVRPYAPTGHRHEAEIEEYLGLSVSFTVHAVDMVRGAAATCHVFPDGPVSKGDMWKAFRGSYGDEPFMRTVAGGGGVYRYPEPKSVAGTNFGEVGFEIDPGNRRLVVFSAIDNMMKGSAGQAVHAANIALGLEETAGLDFTGFHPIGSP
	C441_RS14875	lysine biosynthesis protein LysX	40878	40003	MHVGLLYSRIRRDEKLLLNELRDRGHEVTKIDVRKEQFDLTEPPESFDGLDVVVDRCLATSRSIYITRFLQSYGIPVVNSHETADICADKAKNSLALADAGVPTPNTKVAFTVESAMEIVEEFGYPCVLKPVVGSWGRLMAKIDSESAAEAILEHKSTLGNYEHKVFYIQEFVEKPGRDIRVLAVDGEPVAAMVRSSDHWLTNAAKGASVDEFELDDRAKELVKQASDAVGGGLLGVDLMETGDDYTVHEVNHTVEFKALNDAVETDVPATVVDWLEAKVDGEQSLAEVSA
	C441_RS14880	lysine biosynthesis protein LysW	41059	40880	MSDTITAEDPLSGEEIELPSDVEVGEIIDSPATGAELEVVSLDPVTLEEAPELEEDWGE
	C441_RS14885	argininosuccinate lyase	42807	41341	MAGEDGDSEGVIRRDRFSGGPARGFMSSLAADERIFEADLAVDRAHVVMLAAQDIIEAEVASEILAALDEVEAAGHDALSGGEDVHEAIEAAVIDIVGPDGGKMHTARSRNDEVATCIRYRLREDVLSALDAALALRESLLETAAEHTETVMPGYTHLQPAQPTTVAHFLCSYERAVARDCARLMCAYERINQSPLGSAAFAGTPFDVNRELVADLLGFDRVMENSMDASATRDFLAETLSALTTHAVTLSGLAEDLVIFSNKGLVELSDDYSSTSSIMPQKKNPDTMELVRAVAGDAVGELTGLLTTLKGLPRAYNRDLQRAHKHAFRTVDDVAEAAAVAAGAVGSATWPEGELAAAAGDGFSTATGVADLLAMAGLPFRTAHEVVAEAAARSEGTPDVATLDAVATDVLGESLFTHVTAEAVEAALDPTESVASRDSVGGPAPAAVEATLSTARDELSDDAAAVADARDSLAAAAEGLDEEVSSYV
	C441_RS14890	argininosuccinate synthase	44026	42809	MKKVALAFSGGLDTTVCVPILEEEYGYDEVVGVTVDVGQPEEEFEEAYETAEALGLEHHVVDAKQEFAQLCLDSVCANADYQGYPLGTALARPVIAKAILELAEEQGCDGIAHGCTGKGNDQLRFEAVWRASDLEVIAPVREMGMTREWEIEYAAEKDLPVQGGNEGVWSIDTNLWSRSIEGGNLEDPGYVPPEDIYEWTDQPSDETELIEIAFEDGYPVAVDDEELEPLELISLLNEKAGKHGVGRTDMMEDRMLGLKVRENYEHPAATTLLNAHEALEGLVLTKEERDFKATVDNEWSQKAYEGLIDAPLVGALNAFVEKTQERVTGTVTIKFEGGQARPVGRESEYAAYSESAASFNTETVDGIEQADATGVAKYHGFQARLANQSAKKQKPELAADGGSDE
	C441_RS14895	cation:proton antiporter	45763	44549	MAAALLEFGYLFAVLAVVGAVALRLGLSVIPLYVVGGVVAGPYVAGRFGLPYVPNGEVVTILAELGIVLLLFFLGLEFSLDRLRASGAKIGRAGVIDLAVNLPIGVAIGLVLGWSPVEALLLGGIVYISSSAIVTKTLIDLGWIADPESEPILGTLVFEDLAIAVYLAVVTSLVLGGDGGVAAIGRSLAIAFGFLGLLFVAVQYGTALFARVLDVENQEAFVLRALAVVVPISGAALALGVSEAVAAFFVGMGFSTSGHRERLEHLLVSVRDVFAAVFFFWIGLGTDPTLLAAAAVPLAIAVVVSTPSKVLSGYLGGRAYDLSAHRSLRVGVGMVPRGEFSLVIAALAAAGTTPVMREIIPAFAVGYVFVMSALGTVLMQRSDLVERLVFRGGAADGDASTESA
	C441_RS14900	TrkA-C domain-containing protein	46248	45763	MTVYESDLPGVGKKHEVELGDGSRLVIVTHNTGKREVFRRASADSDSEKLFELTDKLARQVGTLLEGAYFQPVQTETIETLLGDNTLIEWVEVGADSDIAGKTLGESDLRQATGASVIAIERGDEVITSPGGDAMVEAGDTLVVIGPKTACRDFVALVKGT
	C441_RS14905	hypothetical protein	46894	46292	MGRPSTAEVKRRLVHASGSGMPLLYLLGLVEWRTLGYLFVFLAAVVSVLELLRLFGGLQWAVYDELTREYEQDNVAGYALYVYSQTAVALVFGPHIAVPGMLMLTIGDPISGLMGSAPVGELKSARTLAAMFAVCFILAAPFVIPVSGVAAGGLAAAAGAAGATLADGAKPVVAGYVIDDNLSIPPVACTAIAVTLWLLA
	C441_RS14910	glycine--tRNA ligase	48685	46901	MSEGDESAALTELAKRRGFFFGSSEAYGGVGGFYTYGPQGAALKSNVEEAWRERFAVQEGNLEIEAPTIMPEPVFEASGHLDGFDDMLVECAECGESHRADHLIEDNSELEDAETLSPEEAAEKIADLGLVCPTCGADLAGQSVEDFNLMFETNIGPGSSTPGYLRPETAQGIFVEFPRIKEYARNSLPFGVTQVGRAYRNEISPRKSIVRTREFTQAELEHFIDPERDEADLSAVEDVEVLLYPATEQEADDGDYVETTIGEAVEDGIIGNAWLGYFLGIAQEWYETVGVDMDRFRFRQHLAGERAHYSSDCWDAESEVDGDWIEIAGFSYRSDYDLSKHGEYGDDDFTVFQQYDEPKTVERAVVDPDMATLGPEFGARAADVAEALETLAERDPDAFDADEVTLDVDGEEVTVDTDVANFSVETQTEAGEHITPHVVEPSFGIDRTVYTLLAHAYETDEVDGEARSYLSLSPSVAPTNVGVFPLVSNVDELVDLADDVAEELRAAGFAVVYDDSGSIGRRYRRQDEVGTPFCITIDRDGLEGDGANTVTIRERDSGKQVRLPVDDLVGTLVGLRAGTASFDDVLDDNEVVEA
	C441_RS14915	CBS domain-containing protein	49532	48678	MKVADAMTRGEEVVTVSLPGTRDDVLEYLQERGFSSVPVVKETDEGTKYRGLISREDLIEHPDEDQLAVLVREVPTASADDDLEAVAATMVSEGARRIPVVDGDAIEGILTVTDVVRAIARGDIDGETEVGDLATRDVNTTYVDVPLHIVEREIFYANVPYAVVLDDEASLAGIVTEVDIIEVARVVEGEAGTGDSVANQDDEWMWEGIKAVGNRYIPTRNVEIPAEPVSKFMSDDLVSVATRVTAKDAAQTMIREDIEQIPLVSGDELIGVVRDVNLLEALYE
	C441_RS14920	hypothetical protein	50255	49665	MAELGDDETPEVERIAGEADRRREAWGATLDDMAAMADDFEDEGWTTVRIAAGDSGPFGPSSGKGDEGAFGLAYVIPGDKAETVAELFEATTFPEYEVYRAENDGRVYIVTALFSPETETAVFIAGAWDLREALECATVAVEEGRMYSYLQKLDGTIVGVVEHDDPEKFFPNLDAIRRYAPNGGDGDGDGETDDGN
	C441_RS14925	hypothetical protein	50762	50316	MEFDPRRFGVKAIDAVAYAVALTGVVFVVTAVVSTLAGNGLPGAKWLMFFLGFAMFGYSSLKVRPKAAWKRGDGSGGTGGTDGGLFSGSDEPVGVEKLVGDALDAILPPRLRPATGDERPSSGVKLLLASVCILAASYAMEVVFEINY
	C441_RS14930	ABC transporter ATP-binding protein	52099	50765	MSTTPTEEERPTTARGETILEVNDLKTYYEDGGLLGSNPVKAVDGVSFDIQRGETLGLVGESGCGKSTLGRTLMRLEEATAGEVKLNGTDITTLSGSDLKQFRKDVQMVFQDPDSSLNERMTVGEIVREPLDVHDWKTPSERRERVRELLETVGLQEQHYYRYPHQFSGGQRQRIGIARALALEPEFIILDEPVSALDVSVQAKILNLLEDLQNEFGLTYLFIAHDLAVVRHICDRVAVMYLGNMMEIGPADELFDEPANPYTHALLSSIPEPDPTVERDRITLRGTPPSPRDPPAGCPFSTRCPVKIRPAAYRDMDPDVWERIEIFREVLRERSRADPSLSDRVRKLLGRESHRAGMDEIIPELFGDLDVPSDVMTHVREAADYAENDDEDAARTYLREEFGSVCDHERPEQLSVGDRGRLSLCHRHDAEYEEPATVFETLVR
	C441_RS14935	ABC transporter ATP-binding protein	53175	52096	MSTEQARSTRTGGEPLLSVENLRTSFYTDKEVIRAVDGISFDIFRGETVGIVGESGSGKSVTARSIMRLVENPGRIENGRIMYDGEDLLDKSPKQMRSIRGGSIAMVFQDPLTSLNPVYTVGNQIKEALRLHRGLSGSKATKEAIELLEAVGIPDAHRRVREYPHQFSGGMRQRAVIAMALACDPELLICDEPTTALDVTIQAQILELLEELQEERDLGIMFITHDMGVIAEIADRVNVMYAGEIVESAPVVELFESPKHPYTQGLLNSIPGQGLDENERLATIEGDVPTPNEDPTYCRFAPRCPKAFAECDTVHPEPVDVGDGAGDHRASCLLYPEDLPTEEAVAVHREGGQRGGDTR
	C441_RS14940	ABC transporter permease	54611	53172	MSTTTETEIPLRQRVAENPQPALIWAAVGAVLIGVELGAILQVVGAVAGVVVNLLPGDPGASAVQSLQAAFNAVPTLVSRDVIPNQGYWNGTGYENTFLGLSPAVAWFIRVAFVYAYAFAVLAWAWNGYTRFRRHYRRVDWTPRDDVVNRFRGHSWGKFGLVIVITFVVMAVFAPALGPTTMERNILQPYDYEVTYWSEDTQSTETVLVGEANLGSGSQGAGDENVAPLTYDDYGRFHPFGTATNGKDLFTQVVFGARISLTIAVVAMGIAGLIGLGLAMITAYYKGLADLATVLVSDSVQALPVIMVLILMLVIFQNTWVRELYDGAVLIILIFSVVYWPFIWRSIRGPALQVSEEDWIDAAKSFGQTPTQVMRKHMAPYVFSYMLIYASLSLGGIIISVAGLSYLGLGITAPTPEWGRLIANGQQYVASPSWHISLVPGLLITLVVTGLNAFGDGIRDAIDPQADTGDEAAATGGGA
	C441_RS14945	ABC transporter permease	55667	54618	MSRWQYFLRRVLMSIPVVIFGTTITFALIRLGPLDPVSAILGTQYNPQAAEQIRTNLGLNQPLWSQYLDFMYELFTFQLGQSWVIAPGTTAYELIEIYAPRTIWLGFWSVLIALFVGIPLGFYAGLNPNTPSDYVASFGGIVWRAMPNFWLAIMLVTALSQLGTWTNGLFTWQTWIVRTNVVTPPALGFFQSPVEQFLADPGGWTESFIRATKQIAPAALVLGSASMGNEMRIGRTAVLETINSNYVETARAKGVSGRSLVWKHIFRNALIPLVPIITGEAFLLLGGSVFVETVFAINGLGWLFFNAAINGDLPLIGTLMFIFILILVGTNILQDFLYTIIDPRVGYDG
	C441_RS14950	ABC transporter substrate-binding protein	57705	55879	MPDTNKLSRRRFLKATGGAATAAALAGCTGGDGEETTTESGGGETETTQEDTGTELSGSVFNRILDGTITTMDPVAATDTSSGILIQQVFDCLMSYQNALPTVENELAADYTVSDDFTTYTFELADATYHNGDQVTASDFIYAWERLAASENSRRAYFILDSVGVEHEEDDEGNYVPGTLGLEVGESESELVVNLAEPFHDTLEMFAYTSFAALPEGILGDIEEYDGEMEYTEFASNNPIGAGPFEFAFWEQGTAAAVSKYDDYYGQVAQVDNVRWQVIEDDTARYNYAMNENADYFGLPTAQYDPGLVQVESTDEYGREVGQYGPVRNGKTLNYVGVPTLSIYYVGFNMEKVPKAVRQAFAYVLNQDQMVSEVFKGRGSPAELFTPPTIFPGGAQAASDLVSSDYPYSAGETDIEAARQVMEDAGYGPDNQYEIQWTQYNNNAWEEMASILRDQLASAHINMQIQKADFSTLLERGRNGQLEAYTLGWIADWPAPDNFLQLLNPPQTDTSEQGPISYVNWTAENGDAYQQATDAYQQVVDNPAPTDEAQQVRNEAYVDIETANWEDVAMLPVYNQKEETFWYDTVEIEPFGGMGPSRQKLNNVTLNR
	C441_RS14955	DNA-binding protein	58182	58601	MNARAVTVSEEYLARLEHGADWREEIEEFCARKGIESAWFNAMGAVQDAELWFYDQTDQEYQSVTFDEPLEVAACVGNVALLDGEPFAHTHAILSRRSGQALAGHLDSATVFAGELNLRAFEEPLERDHDAVTDLDLWL
	C441_RS14960	DNA polymerase II large subunit	58604	63700	MREEETRYFRRIEARLDEAFELAEAAKATGYDPKTEVEIPVAKDMADRVENILGIDGVAERVRELEGEMSREEAALELVTDFVDGNVGDYDSREGKVEGAVRTAVALLTEGVVAAPIEGIDRVEILENDDGTEFVNVYYAGPIRSAGGTAQALSVLVADYARSLLDIDEYKARSDEVERYVEEVNLYDKETGLQYSPKDKESRFIAENMPIMLDGEATGDEEVSGYRDLERVDTNSARGGMCLVMAEGIALKAPKIQRYTRQLDEVDWPWLQDLIDGTIGKDDGKAAKADDAGDDADEADEADADPDADADDAESDAPDGPTRVEPATKFLRDLIAGRPVFGHPSAPGGFRLRYGRARNHGFATAGVHPATMHIVDDFIATGTQIKTERPGKAGGVVPVDSIEGPTVRLANGDVRRIDDPEEAEELQNGVEKILDLGEYLVNFGEFVENNHPLAPASYVFEWWIQDFEATEANVQALRDDPAVDLEDPTVEDALSWAAEFDAPLHPVYTYLWHDISVERFDALADAVAAGEVVAAEADGGTTAPLEHDNEPERGLEGTLVLDNTPEIREALEHLLVAHRQTDETLRVPVWRPLARSLGLTDDRERTWELDDLSEHARTWDGGDNAVEAVNEVAPFTVRERAPTRIGNRMGRPEKSERRDLSPAVHTLFPIGEAGGSQRDVGDAARHRGESGKRGQISVRLGRRKCPDCGAFGFKSKCPDCGGHTEPHYECDDCGTVLEPDESGRVYCERCDWDVESAEWQDIDLNTEYRDALERVGERESSFQILKGVKGLTSANKTPEPIEKGVLRAKHDVSSFKDGTVRYDMTDLPVTAVRPEELDVTADHFRELGYETDIDGEPLRFDDQLVELKVQDIVLSNGAAQHMMQTADFVDDLLEQFYGLERFYEIEERDDLIGELVFGMAPHTSAAVVGRVVGFTTAAVGYAHPYFHAAKRRNCFHPETKVWYRDETDRWRYDEVRTLVEERLDEPETDDFGTLVQELDGDVYVPSLTRSGRETIKPVEAVSKHVAQNHLVRIETRGGRELTVTPDHTVIRADKGGFTRIPAHELDEGDALPSPKRVDIDADPAQFDLLAEFLHGESIPAEDLMVRGLGADRIRSLFDEHTEANGYLKPVAERLGRSESTVYNWVSRDSVPASVFVEVLGDVETVVDVLPRELSLGVRRDTATVSRVLDIDESFGTVLGYYAAEGFTRASHGNLYQTTICIPDELARKRILDTVSEALGVDAFEENEWKVTVSSRLVQSLFADVIGCGSRAEDKRVPDSVLTGPEPVLRSFLSAYFSGDGSASSDRVEIRAHTVSDDLKRDLVAALKRFGIASKTYSERRTPQTGAVAEFYDGDEVPTFDSWVLKLTSENAVRFAEEVGFHPPRKSEALASALDDTGVRSQRLFSDGGDTWLDEVVSVEYLESDIDHTYSLTVEDTNSLVANDLHVAQCDGDEDCVMLLMDGLLNFSKEYLPDKRGGQMDAPLVMSSRIDPSEIDDEAHNMDIVRQYPREFYEATLRMEDPDDWEDEVTIAEEYLGTDREYTGFDHTHDTTDIAAGPDLSAYKTLGSMMDKMDAQLFLARKLRAVDETDVAERVIEYHFLPDLIGNLRAFSRQETRCLDCGEKYRRMPLSGDCRECGGRVNLTVHQGSVNKYMDTAIQVAEEFDCRDYTKQRLEVLEKSLESVFENDKNKQSGIADFM
	C441_RS14965	hypothetical protein	66642	66175	MTTYAVLSPPDGSTLHSRERRFAADLCDQLLYLTPGSLDEEPDGEIGDLTPTELANAVYTSTRGRDWNEDDEMYILVEPALLDIETRNAFRRSLRVVFQRFDPEVCFPYDVLEDVGKRAAWLTDSLEAGEIVRPGGVRRQSVTGVDEGQTDLTSF
	C441_RS14970	hypothetical protein	67367	66699	MRVRQRQLLYGTVFGLATFLVGWLITYVLTPSDLLTEFPRWKVTLWVFLSAHFVSISGLQLGGLSSAFTQVDLITQIPTLRSLRVVPILLTALGGVMMVEAMNYTTRFKYLIQNSGALLTGYLAAGLLAFVISEAQPGVALIIVLAVLLAGGAYIGGTVTQRFTAGLPVFAVTSLGGVVLIGLLVVLGGLVVLQSIAPLVGVSLVGVTVGAVLAWTARNVPS
	C441_RS14975	MarR family transcriptional regulator	67657	67433	MPHELNRADKRILRALENGVRNPSWLAEQLDYSRQYVHQRLQLLVAAEYVNNLGHGLYELEELPNGLGQDSKDQ
	C441_RS19140	HNH endonuclease	67761	68234	MGTIVWIMATASTKSMIERPFPKVKDRPTSDVPAIARDGESGMYEVIECPECGSEAFAYLQLRYACRECKVGSRILQKEVNYGGRWERVREWILERDNDQCQRCGDSSVGLQVHHKEKLVWFESIQEANTPENLISLCEDCHGEVEEQPEMACLPVM
	C441_RS14980	hypothetical protein	68904	70679	MLRGIEYRSHIVSELSDRPNTRRELGYGTFNGTRRCPHQTNFNEAWNDRFGPDLRAFVTEVVAYVREWAYDNNRLIETTELLVPDERDETQELTKDQIRRIVNEMVGYITPNYSFNREGGVSHDKNVFFKLLAHCALTSSSVHGGGDTFEWQQIDDDDPPHGRTVLDLVKSLSAGEMLSMYADAIDGVVEALDKQVGLYDSPVPLAIDTTTIESDAKWKRVTIPSIADPEYHGWSDRKKKDTYAYIEEEGIECLVGEDPEKIRKARFHDDEKREAAERINDVVRYVHGTKSGDEFKYAWEFGAAAIAHPSCPLIYAMEPLERKDELEDHVERFIERGQELVTVSEVYMDSAYSQVAVQQLFHYGNAFRTEDQFNIPYVMNIREEDSVKKAVLQEKPGRGDITTRMDESEGDISVVKNYRQHSQEHGYGATTLVGLPKRDYENGGVVDVKDPVTDRVAFSTSRTDIDAENAIELLRGPDSESFSDPVRRRKAKHERGYTNRWLIEIGFEKTKDFLAFTKSGHGGVRLFYVLYASLLFDVWMTVDRAIKHEEYELGFDVETYDEDDSVVYATSPRISADVLSTIVANYLRPVT
	C441_RS14985	hypothetical protein	70999	71286	MADETEPTVGMTVYAEDGSKLGSIRGFDEDGFYVTIREGLAGMSIEHERAGHEFGEAELMWRCSDCGEMGDLDELPDTCPNCGAEREQLYYWTED
	C441_RS14990	histidinol dehydrogenase	71423	72691	MDIQSLDALDESELASVLDRDAGIDEIRADVRGIVEEVRDRGDDALREFSEKFDGVEVDTLDITARTERAAEAIEPELREAIEAAIDNVRAFHERQVRTDWTDSFGGARLGRQFRPLRRIGAYVPGGSATYPSTSIMTVVPAKVAGVEEVVVVTPPAEELNPVTLAAIGLAGADEVYSVGGAQAIGALAYGTETIPPVEKVVGPGNRWVAAAKAEVRGDVAIDMIAGPTEVLVVADETASPRLVAAELVGQAEHDPHSSVVAVTPDESLARAVADEVEAQVPDRARPEIIREALANETSGVFVAPSMDEVTAFAEAYAVEHLVVMTADDEATVDAIDSAGSVFVGEYSPVAAGDYASGTNHVLPTGAGAKTTGGLSVDSFVRSRTVQHLDRDSLDSLSDTIVTLAELEGLEAHAESVRKRFE
	C441_RS14995	SDR family oxidoreductase	72773	73552	MSVLDEFTLHGKTAIVTGSSKGIGRALAVALAEAGADICLVNRSEREGRLAAEEIAAETGVETLAVPADVTDEDDVEAMVEATLDAFGSIDILVNNAGIARTAPAHEMSLETWNEVLQTNLTGVFLCTKHAGKAMIDGGGGTIVNMASMSAFVANYPQEEVVYHASKGGVVSFTRQLASEWAKYDVRANAMAPGYIRTEMVDELLAENPDMESAWLSEMLMEEMAPPEDLGGTVVYLASDASSYMTGETVVIDGGYTVR
	C441_RS15005	extracellular solute-binding protein	76044	74863	MRKHTNSQPSARATGRSRRRFISAAGATALAGLAGCTGGGGSDGDSGGDASSGTTTGTEDTTPPKPDSITVRAWGGAWQENLDKHIAQAFTDETGIEVEYDNSTEEEMQGKIRTAITQDRTPPVNVNWSLSKTSYRSYQMGLMEPLDTEVAPNLEGLLGASKPEVEDAEWPFVNLYSYTYALTYNTDLVSSEPTSWSVWWDDEWENSIGLYPGGHGITPLIAKMTGTELGPVEEMTPVWDEYTALKPNVGTIGDDSHLTQNLRQGEVAMSVMLPANIINAQDDGAPVDYTIPEEGARAGRDTMWTPTNQDERYVYWGQKFIDTAANAENLGPWSTELGVAPLHADATIPDWMRDSVAFPTSEEQFNQMITVPLDLLIEHQAAWESRVNEMMQA
	C441_RS15010	DNA-binding protein	76432	77082	MYEATLRIDHQSPYADVTLGKDVHVEMWCNQYCDLVYVSGSDIETPVETFDDTVGIQEIVYKDEEAVLITDSCLLDYRDNLLEGYLQPHQCLSLPPLTYSDVALFARVLALTEEQLSGVYHSISDSHRVTVEAKREIRSIAPDIPILMLDSALPTLSDGQQRALSLAVEMGYYEIPRGSTTGEIADEMGVSRRTFEEHLRRAENKIIKNLLRYFLT
	C441_RS15015	ABC transporter ATP-binding protein	77181	78272	MTDSSETVVRIDGVTKEYGTLRAVDDVTIPITDGEFITILGPSGAGKTTLLHMIAGFQKPTSGEIYIDGRPVSDEPPYERDIGLVFQSHALFPHMTVKENIAFPLKMRREHTDDIDRKVEDVLELVRLPVDYADKPVDELSGGQQQRVAFARAIVYEPTLLLLDEPLSSLDKKLREEMRAELTRIHEETELTIVHVTHNQTEALSMADRIAVINGGGLEQLDSAQDIYASPNTPFVADFIGNTTLLSGSVAGVDGDVATVSVADGTVRVPAATVDGLSDVVVAIRAEQVALDADCDNTYPATVEQVSFEGDRTQYHVFVPAFGETVRLIDQSADARVVHDRGDSVTVGWNVGDGFVYPDEDDE
	C441_RS15020	C-terminal binding protein	79304	78345	MLDPDWFGDVESERAHFERLLGSSVVVDAVDCTDAEIPDAVGAADLLLSHDTGVSAESMDATGCSVVSRYATGIDGIDVEAATDRGVRVTRVPTYCNDEVGMHAVSLALALVRGLPTYDAAAADGRWHWADAMPIRAVSELTFGLLAFGNKGRSAGEKALALGFDVCAYDPYVDDGDIEAAGVRPVGFEALLAEADVLSIHAPLTDETADMIDADAIDALDDDAIVVNTGRGRVVDEGALLDALRGDRLRGAGLDVLRAEPPNPENPLLDREDVIVTPHAAWYSTRTAEKLRRLGTETAVAAYRGDAVEGLVNPEALDR
	C441_RS15025	pyridoxal phosphate-dependent aminotransferase	80547	79396	MMKRPGLSGLSTRMPQSGIREVFDAAQSYDDLADLSIGEPDFATPEPIAAAVSEAVGTGASSYTETVGRPELRAALAEKLAVENGIDAAPESEIIVTPGAMGALFAAVNVLCDPGDEVLVPEPYWPNYHGHVASANARLAPVSTDEAFVPTPDAVEAAVSDDTTAILLNSPGNPTGAVIPPDRLRALDDVAAEHGLWVIADETYEDLVYDGATHHSLASDGDRFDRIVTVHSFSKSYAMTGWRIGYASAPERVIDAMRVLQEHTVSSVPEPAQVAASAALANRYVVGELREAFAERRRLVLDRLAAIDGIDPGTPRGAFYVFADVSAHTTDSRAFVERLMSEAGVASVPGAVFGAAGEGYVRFSYAADVETLTTAMDRLERAL
	C441_RS15030	RidA family protein	81045	80602	MTRYAINPPELKDARSIGYNHAIIDSQQFYMAGQVAMDADSNVVGDDIETQARKAYENVGILLDAIGMTYADVAKVTTHIVDAKEHYYDGYKEVYLETFEEPYPCHTVLGHDQLANEDYLVEVEVELPLTEADVDAIEPDGDVVREL
	C441_RS15035	Zn-dependent hydrolase	82354	81107	MNIDTDRLRRDLQENAAFGDVDADGGVGRTVLTGSEADRGVRERFVERLEAAGLDVRVDAVGNIFGRWTPPSCDPSAAPVAFGSHLDSVPRGGIFDGPLGTYGALEGVRAMQEADVAPARPVEVVSFTEEEGGRFGVGTLGSSVATGKMGVDEALALEDDDGVTLRDHLDRVGFAGSDAVDPAEWDAWMELHIEQGTRLTGANAGVGVVDSITGITNCEVAVTGEADHAGSTPMYERSDALAAASEFVLDLERAAEELATTSEAAVGTAGKGTIEPNARNIVPAEVRLQLDIRDVEHETMDRLVERCRTSLARLERNRGVETSMSRYRDSPPSRMADRCLAAADAAAATRSVDALRLHSAAMHDTANLAAVTDAGLLFAPSRDGVSHSPREWTDWDDCATATGVLAETVRSLASD
	C441_RS15040	lactate utilization protein B/C	82469	82975	MSDTDTQLFASSLAAIDVPLTRTDTAGFASTIDSLVTEPAVGVPLHLEGVSLDDTVVQTPPTPRLLREAETGVTGVGHAIAEHGTLVIDSDDAGTEPVSLYPPTHLAVVRESDILPDVASATASVGERFAAGGSAVFATGVSSTGDMGALVEGVHGPKHVEVVVLTDQ
	C441_RS15045	4Fe-4S dicluster domain-containing protein	82972	85182	MSAQSERRRKARKLRELLDAEGDAVYENVTHLNQGRYDAIERFDEFETLRTEARSIKEAAIENLPSLIETLRESVEANGGSVYVADDAADANRYIRDVAEANEAETLVKSKSMTTEEIELNESLEAAGVDVWETDLGEFVLQVADESPSHIVGPSLHKSREEVAALFNDVFDPEVPFETAEELTEFARDYLGDRIREADVGMTGANFVLADSGTITIVTNEGNARKSAVTPDTHVAVTGVEKILPSAAELEPFVNLISRAATGQDISQYVSMLTPPVETPTIDFENPDEPLGSGDAEREFHLVLIDNGRLAMRDDDHLRETLYCIRCGACANSCGNFQHVGGHAFGGETYTGGIATGWEAGVEGLDSAAEFNDLCTGCSRCVNACPVKIDIPWINTVVRDRLNGEATPSDLEFLVEGLTPDAEGTVTPQKRLFGNFGTLARLGSATAPLSNWVADLGPVRSLMDRYLGVAPDRELPTFQRETLVDWFQSRRPRAPNATATRKVVLYPDAYTNYVLVDRGKAAVRTLEALGAHVELATPIESGRAPLSQGMVATATRQAEAVASDLAPYLDSSFDVVVVEPSDLAMMRREYGKLLDDETHARLSEHSYDVMEYVFGLLSNGADPAALAAPDAPVAYHSHCQQRTLGVETYTEAVLDDLGFDVVTSDVECCGMAGSFGYKSEYYELSMDVGAELADQFADAGDRVVVASGTSCTEQLTDLLARDVTHPVELVAPDEAP
	C441_RS15050	carbohydrate kinase family protein	85285	86187	MADVLVLGDAIVDAVFAGLDRYPDRGEELVAPSFELRPGGSAGYASLGLAALGSRPAAVTYVGDDVLSTHWRTFLDARGVDTSRVVEQPDATVSVAAGFLFESDRSFVTHRGAMTDGAIPAVTPDGFDALFVAGLSQAPYLWGDDAVAIAREFSARGRPVFLDTNWSPGDWLSTAEALLPHVDTLFANDAEARRLSGCDDLVAAAETLVADGADACVVKAGDRGCLVADGQSEATWVETEPAASVDACGAGDFFDAGFIHARFAGADRPAAAAVANRCARAAITNFELRAKLDAIADLSE
	C441_RS15055	ABC transporter permease	87039	86230	MSGLLRRFGTDHPYLAAFTLFEFVFLILPSVIILVVSLGANQIISFPPTELSLRWYASLIQEPGYLEPFFNSVMVAVFCTALAIPIGVMTALGLNRYDVRFEHGIQIYLLLPFTVPLVVSGFILLIIFGRLGWIAELWAVGLALTIINIPFMIWSVSSSVNAFDSTLEDAAQSLGAEEIQTFRYVTLPALMPGVISGSFLMFMLALNEFIVSLIITTTATETLPVAIYGAIRGNISPQIAAVASIYVIIAIVAIVVADRVVGLERFLHS
	C441_RS15060	ABC transporter permease	87941	87036	MDGLIAAKNRLPLDTSSVADRFGYVLIAPSILLVSFLAVGMVMLAWYSVLTYDTIEIFVYELTLDNWMRLVETGAFHTVFFRTLLYSALVTVGSVGLAVPYAYLVVRTRRPVFRYVLLFGLFVPFFTGVIIRAYGWLIVLGKNGLLNWGLNALGIETVSIIGTPAAIVVGLLQYLMPFAVLMLTPAIASIDSDLERAAQNCGANNWETFRHVVLPLSRPGITAATIVVFTLSMANYAIPNLLGGGTNSFVANFIYSKVFDMMNYPFAAVLCIILVLVASVFVFAVFKLYGTGTLGVEAGEQ
	C441_RS15065	ketopantoate reductase family protein	88284	89180	MRILVFGAGSLGTLVGGLLAPVHDVTLVARDPHAARVSSAGLDIVGAESAHVSPAATTTETGHDADLALVTVKSFDTAAAADALADCDVGAVLSLQNGLTEETLASRLDAPVLAGTATYGARLVEPGRIECTGVGRIVLGALDGGPDPLAERVGKAFRDAGLNALVATDMPRRRWEKLAVNAGINAVTALSRVENGALAGDDASELAHRAARETARVARLERVSLPNRVAREALDRVVEKTAANRSSMLQDVAAEKRTEVDAINGAVVDIAAEHGFEVPTNRTLAALLRAWERGAGLR
	C441_RS15070	sulfatase	90761	89220	MTAESPENVLFVVMDTVRKDHLTPYGHDRPTTPGLDRFADEATVFEQAVAPAPWTLPVHASLFTGMYPSQHGADQENPYLEGATTLAETLSAAGYDTACYSSNAWITPYTHLTDGFAEQDNFFEVMPGEFLSGPLAKAWKTMNDSDALRTLADKLVSLGNTAHEYLAGGEGADSKTPAVIDQTIDFVDGSEEFFAFVNLMDAHLPYHPPEEYKERFAPGVDSTEVCQNSKEYNAGAHEIGDDEWEDIRGLYDAEIAHIDDQLTRLFDHLKETDRWDDTMVVVCADHGELHGEHGLYGHEFCLYDPLINVPLMVKHPGLDADRRDDQVELVDLYHTVLDSLDVEGGEPANPGDDAVGLDRTRSLLSADYREFAQASNDDPGQRRDGEYAFVEYSRPVVELKQLEEKASSAGITLPEDSRFYSRMRAARRTDAKYVRIDRIPDEAYRIDADPEESENVVDSDDEAIAETEAALTEFEAAIGGAWTDALDTDVSDDSVDQMDDEAQDRLRDLGYLE
	C441_RS15075	hypothetical protein	91216	90839	MSTETQDGEDDLKERVVNFLRRNFPQIQMHGGSAAIRDLDRETGEVTVLLGGACSGCGISPMTIQAIKTRMVKEIPEINEVHADTGMGGDGGMGGDSRGGSPSFPGDTSDDTTDIEDDQGPQAPF
	C441_RS15080	hypothetical protein	91578	91261	MTDFDPEKFEDKYANYFPELQRAYKNAFETMNDEFDSSLIHGVDQQILNESEPFYEDGDFSVRLPENPAERLTAVEIDDDELEAVLDRYVDEIEGELRRVFGVEA
	C441_RS15085	hypothetical protein	91957	91736	MATANSNEAEYDYPVGYEPEVQTETVELDRRTVERLDALREDDESYDELITELASIFAASELSAARVDSPLIE
	C441_RS15095	polyphosphate kinase 2	93191	94021	MSTDNPRYNDEGVLKKKQYKRELNRLQEELVKLQYWIKEHDLRVCVVFEGRDAAGKGGVIKRITRRLNPRVARVVALGKPTERERGQWYFQRYVEQLPTEGEMVLFDRSWYNRAGVERVMGFCTDEEYEEFLRTCPEFERMLVRSGIVLVKYWFSISDEEQERRFQKRNEDPKRRWKLSPMDLEARSRWADYSEAKDAMFEHTDIDEAPWHVVNADVKRHARLNCISHLLDQIDYEDLTPDPIELPSRQDDSGYERPPIDSQNWVPARFGSNPVDD
	C441_RS15100	DHH family phosphoesterase	95448	94018	MDGPVPELTEHAAACAARLRDADRVLLASHIDADGLTSAGIASTALERAEIPFETVFCRQLDAAAVADIAATDYDTVLFTDFGSGQLDIIADHEAAGDFHPVIADHHQPAEGVETDHHLNPLRFGLNGASELSGAGASYVLARALEPEGRDNRDLAALAVVGAVGDMQDTNGELRGANAGIVDEGVEAGVVEEGTDLRIYGRQTRALPKLLQYATDVRIPGISNNEAGAIEFLTELDVPCRDDDGEWKRWVDLTGDERQTLASALMRRAIASGVPASRIDDLVGTTYVLSREREGTELRDVSEFSTLLNATARYDRADVGLAVCLGERDAALDRARRLLRNHRKNLSNGLQWVKEHGVRVEDNLQWFDAGDEIRETIVGIVAGMAVGTDATRSGIPVLAFADTEGGEVKVSSRGSYVMVRDGLDLSAVMREASRAVGGDGGGHDVAAGATIPKGEVEAFIAEADRIVGEQLAKNPD
	C441_RS15105	MFS transporter	96804	95611	MTGSEAEDGTRDGSWRAVGSVAGWQTAASLCYYAIFAATGFVRDAFSVSESLVGLFLTAGLLGYTVFLFPSGAAVDGYGEKPVMVVGLLALSVALVGVTFAPPSYALLLVTVALLGAAYSTAMPASNRGIVAAAPAGSKNLAMGLKQVGVTVGSGASSLVVTGVAVVAAWQVGFWAIAVFAAGYALLFATRYRGNPGTGRLERPRLAGLGGNRAYVALVAAALFIGASIFSMLGYTVLYVQDVVGTGPALAGGVLAATQVTGSVGRIGAGSLADRLGGPRGAATVALVQLAGSVALFSLLVGAGGSFALTIAVFVALGLTIHGSTGVFYSCLSGVVDDGDIGAATAGGQTALNVGGLVAPPLFGFVVESTGYGAGWALVAGSTVLATVLLFVVRRRI
	C441_RS15110	uroporphyrinogen-III synthase	97549	96806	MSQQVRAAVFRPDDDRIERAVELLDSLGATPVPDPMLAIEPTGATPEAGEFVVLTSKTGVELLDEAGWEPGDAVLCCIGPATADAAREAGWTVDRVPDEYTSAGLVDHLASDVDGATVEVARSDHGSAVLTDGLRDAGADVHETVLYRLVRPEGAGKSAELAAAGDLEAALFTSSLTVEHFLDAAAERGVREEAIAGLNDAVVGAIGPPTRDTAESHGIDVTVVPDEATFEALAVAAVETAAPTYHE
	C441_RS15115	uroporphyrinogen-III C-methyltransferase	98400	97546	MTGDDRSNGDSGESAEGVGTVHLVGSGPGDPELLTMKAARLIDEADVVLHDKLPGPEILGMIPAEKREDVGKRAGGEWTPQEYTNNRLVELAREGKDVVRLKGGDPFVFGRGGEEMEHLADNGIPFEVVPGITSAVAGPGSAGIPVTHRDHVSSVSFVTGHEDPTKDESAVDWDALAATGGTLVVLMGVGKLPLYTAELREAGVDGDTPVALIERATWPDMRVATGTLDTIVDVRDEADIEPPAITVIGEVAATRDRVKQFLQGGGADAVAEADATAGGSGGDE
	C441_RS15120	hydroxymethylbilane synthase	99493	98402	MTTTLRLATRGSALARAQAASVQGALASRRLDVELVEVETTGDRIQDELIHRLGKTGAFVRALDERVLDGEVDAAVHSMKDMPTEKPADLVVAGVPERAPAGDVLVTAEGHDIDDLPEGAVVGTSSLRRQAQLLNYREDLEVEPLRGNVDTRIEKLLATHLQREHEARVENDKERQEKKGKTDHDEAFDETADEWFEGLTELERQALGRKVETEYDAIVLAEAGLKRSGLTEKVNYERLPRTTFVPAPGQGAIAVTAADAEVIDLIRDKLDHPRTRVETTVERTILAELGGGCIAPVGVHALLQGEHVHVDVQVLSTDGSESIKTSRDLPVGNHAHAAREFAAALRDRGAGQLVEAAREEAEE
	C441_RS15125	hypothetical protein	99600	99989	MPAFDSAVRQVGDLVVVALLLFGLTSVVAPLDVFLSSVGVEPPWFAGLAAAALVGLVLLLARPLRLRLVARVWGVGLVVTALWIPLLILLELRGNPVGVLVSWAVCLGVGVALTYPPLWRAAEARLRVE
	C441_RS15130	hypothetical protein	100035	100310	MRERTPVARAGSPRRSACRTVFGLRGDDSNVNRSLHPALVFGVAFVVALPLGFIFAPDPTGVAPLFLTAGLTVVIGLPAYLGLSRATGPES
	C441_RS15135	glutamate-1-semialdehyde 2,1-aminomutase	101682	100345	MNHDESRALYDRALSVLAGGVNSSVRATQPYPFFVERGDGAHVIDADGNRYVDYVMGYGPLLYGHDAPEPVQSAVQKHAAAGPMYGAPTEIEVEHAEFVERHVPSVEMLRFVNSGTEATVSAVRLARGVTGRDKIVVMQGGYHGAQESTLVEGGPGGAKPSTPGIPSSFADHTIPVPFNDEETVREVFEEHGEDIAAVLTEPILANTGIVHPVDGYLEALRDVTEDHGALLIFDEVITGFRVGGLQCAQGKFGVTPDLTTFGKIIGGGFPVGAVGGKAELVEQFTPGGDVFQSGTFSGHPVTMAAGHEYLKYAAENDVYGHVNRLGEKLRAGITDILEDQAPEYTVVGTDSMFKTVFTRHGAAERADACADGCAQVESCPNYDACPKTGADVSNAETDRWERVFWQEMKDHGVFLTANQFESQFVSYAHTDEDIEETLEAYKAAL
	C441_RS15140	CPBP family intramembrane metalloprotease	102528	101821	MVTVAVLGGLAVALFGMAAVGLLADRYLAEPDGLRADLLVSDANKWAVFALLCGYVLVVEGRPLSSMTGRSLAPLAFVAVVGGGVFVLFVANAVTTPVFDRLGVGGLDEGMAGLASLSVRHRLFVAGTAGITEEVLFHGYAIERLLELTGSPLLAGGVSFAAFTASHAVGWERGAVARIAVPALLTTVMYLLVRDVVALVCIHALNDAVGLLLAGSVEDAGDAEGADAAADGTAR
	C441_RS15145	P-II family nitrogen regulator	103054	102683	MSDSDLPNDGDIKMVMAVIRPDKLSDVKTSLAEIGAPSLTVTNVSGRGSQPAKKSQWRGEEYTVDLHQKVKIECVVADIPADDVVEAIADAAQTGEKGDGKVFTLPVESAVQVRTGKTGRDAV
	C441_RS15150	ammonium transporter	104428	103058	MLTPLQTDLASVVEGVNLVWVLTVTFLIFFMHAGFAMLEAGQVRAKNVANQLTKNLLTWSIGVIVFFLLGAAVSSIVAAFTGGPATTISGAFMSLYAPEASATTAWVDWLFGAVFAMTAATIVSGAVAGRARLRAYLTYTILIAGVIYPVVVGFTWGGGFLSALGFHDFAGGMIVHGMGGIAGLTAAWIIGPRMDRFKPDGTANVIPGHSITFAVLGTLILAFGWYGFNVGTAAAPLAYADGGVSLGSFAYVGRVALVTTLGMAAGAIGAGGVAMYKTGKVDTLYVANGVLAGLVGITAIANDIVWPGALVVGLLAGAQLPVVFEFVEKRLQIDDVCAVFPVHGSAGVLGTLLYPVFAVPLWHDGASFVSLAVPQVIGVGVIAIWTFVATAVVFGGFRAVGQVRVSSDHEREGLDTAEHGVDTYPEFGSPDADTGIRTDGSGVPSGDGFMTTGRED
	C441_RS15155	P-II family nitrogen regulator	105173	104808	MSDEADEQGIKMVMAIIRPDKLSDVKTSLAEAGAPSLTVTNVSGRGSQPAKKGQWRGEEYTVDLHQKVKVECVVADIPADDVVEAIADAAHTGEKGDGKIFVLPVESAVQVRTGKEGKPAV
	C441_RS15160	ammonium transporter	106588	105170	MGWSVVIPLQVDPGVIAQGVNYVWILVVSFLIFFMQPGFALLEAGQVRAKNVGNVLMKNMTDWALGVLVYFLVGAGVATIVGGLTSSGGFDVAAAFSYIGDSGAWIDWLFGAVFAMTAATIVSGAVAERMDFRAYIVFAATITGFIYPVVQGITWSGGLLSSGGYIGAALGVGYLDFAGATVVHMCGGVAGLVGAKMVGPRKGRFDANGNSQPIPGHSMLLAVLGTLILAFGWYGFNVGTQATVLATTESGGLEFMGAALGRVALVTTLGMGAGAVAAMIVSTSYQGKPDPLWMANGLLAGLVAVTGAVPHVTWWGGLILGALGGAIVLPAYRWTVDSLKIDDVCGVFAVHGVAGAVGTALIPVFAVSGFSGTQLVMQVVGVVVIAAWTIIASAIVFAIADAVFGLRVSEEEEEEGLDAGEHGVSVYPEFVGDAGPDGALGSPTATDGGSDVRTDGGVVKDETVEANGGDSQ
	C441_RS15165	porphobilinogen synthase	107938	106955	MEFTDRPRRLRTDGIRPLVSETTLDATDLVAPVFVDATTDERVPIESMPGHERVPVAEAADRVAEVREAGVEAVIVFGIPESKDPEGSRAYARNGVVQEAVRAITAETDAYVITDVCLCEYTDHGHCGVLEDHAEDDPTLTVENGPTLDLLAETAVSHAEAGADMVAPSASMDGMVGAIRAALDDAGHDEIPIMSYAAKYESAFYGPFRDAADGAPAFGDRRHYQMDPANAREALREVALDVEQGADVLMVKPGLPYLDIVRAIREGYDHPVAAYNVSGEYAMLHAAAEKGWLDLDAVARESLLSMKRAGADLIITYFAERVARQLD
	C441_RS15170	hypothetical protein	108042	108554	MSAFTAQLPHFLRDLLASDLALVALFFVFVLEGAMLLYVAPSELLVPGALALVGDRLLLPILGVAVLGATVGQVGLFLVAKRGGREYLLSRSWFRVSEDSLDRFDGWFDRWGPVVVPLSNAMLFTRGMLTVPAGLSGMSAKRFLALSALGTVAFESALAALYVFGGQVLA
	C441_RS15175	PHP domain-containing protein	109669	108875	MDDSPPVADLHLHTTASDGRLTIDALPDAARAGGVDVVAVTDHDRYHPDLDAPVVERDGVTVVRGIELRVDAGDRRVDLLGYGLRERPALVEVVERLQRNRVERAREIVAAVEAETGVDLDIDIHDGVGRPHVARAVDASEAPYDYQGAFDELIGADGPCYVARELPTFDDGVSALRDACDVVGLAHPFRYRDPAGALELCADLDAVERYYPYGFDVDCDLVEEAIERYGLLATGGSDAHDETLGRAGPPETDFARFAAAVDGL
	C441_RS15180	hypothetical protein	109802	110086	MRLNGLGDAIDRHEYPISSTDFAQRYGDKVIELQNGQETVAQILARLGDETYTCPQDVRDALFTGVGHEAIGRRYYSDRDPSPLGENGPEMVSF
	C441_RS15185	hypothetical protein	111239	110232	MARPLRFRYAPGRWDESRITRDVFQPLDANLGAEMGAPWYAPPDGYEARRFDMDNGDTALFAWSDDHAYWIGNTETPSSLWRTDKEGFAEAPFEVSRWAQRELIAELFDQSPWLKPYPHLSWFFLPVFLSKDGRETTREFFRDHAAGFPDATREEALAFYESFFATGVLDEYREVMAGKLGTSEYFDPIRMAAAMGEFDVAYLLDEAGYDITPEIAVTTGHSIDFRAENTPAGGALIEVTRPLPPNRRSVSNPIAAIRDTAQTKTNGEGQLAEHGGGVTLFVDCSSFPDDDWAAIMGERPDVRHRPAVVFRLRPSGEVEGYSKGSVPVDLPWLSD
	C441_RS15190	hypothetical protein	112309	111614	MNDAPEYGETWVYESIVGALPGVNIGEAGAIALQIAVFEVAVLVFAWVYDLWAAAVAGTAAIVVAAAGSVVMLRMGEWTRAARVPAPYRRLLFGSSIEVVLGVLAFVALVTHLFVFDPRQPGTPLMTTLFGPEPPVVVVYLTLLVLWDLCYRIGTSWWAAVVGLWGAVRYRFDGPTAKTVRRVNLLNVGFAVAQVLLLPFVADQPVLLLAVGGHVVAVTVVSVTAAALTRT
	C441_RS15195	NAD-dependent epimerase/dehydratase family protein	113333	112395	MRVLVTGATGFVGRHLVPLLLDAGHDVVVFVRDAARYDGPPGADVVEGDIFEPATLDPAMAGVDAAYYLIHSMHAGGDFEARDRLAARNFVDAAESAGVGRIVYLGGLGEDRDRLSAHLRSRREVEHILASGAPALTTLRAAIIVGAGSASFEMVRQLATRLPVMVTPQWVETRCQPIAIADVVAYLAGVLDHPETAGETYEIGGPDVFTYREMLQRVGAQLGHAPRIVPVPVLTPRLSSYWIGLVTDVDTGVARPLIEGLKNPVVVGDDRIRDIVEVEETPFDAAVERALREERGTRENAAEPEPEPTTPT
	C441_RS15200	zinc/iron-chelating domain-containing protein	114329	113445	MRVDCEGCAGCCIDWRPVAPVALDHERRGPRAPLDDTYNLVPLTRDEIRDFVAAGLGDSLTPRLWEAPPGEGVEIDGVELAAIDGNPAFFVGMRKPPKPVAPFGLERTWLRACAFLDPETLQCRIHDTEFYPDECAEYPGHNLVLEQETECERVERHHGGERLLDDAAPDDLHGLLLGPHALGAKLFVHPEPERLAGTIEHLETRDLTPEDRAEFVGVAVGSHPGSTEVDEERASRARAKTLESESWAGETVAAWNAVAGRLGSAAADAPDPDEVEVARGAPETPGWDAVRGGD
	C441_RS15205	hypothetical protein	114447	114650	MTSEPCDACGKGVRIAGGIGDLWNFPTSSSGGMTLELVDGSEHFLCFDCMERLPGDREPTAEDVAAL
	C441_RS15210	hypothetical protein	114879	115085	MDSEPWADYAKMSTESGGGILRRRWATLSKKFSSLSTWEKLSRAREVLKTAYWLLKVLIALSTLVVLL
	C441_RS15215	ATP-dependent DNA helicase	115419	117329	MDPSRIIDSFPAPSFRGAQERALRDIRDAFADGNDVVLVRAPTGSGKSLLARAIAGSAATVDETSPAQATDAYYTTPQVSQLDDVAEDDLLSDLKIIRGKSNYNCIVCGEEDTPVDRAPCARKRGFDCSVRHRCPYFSDRAIASNRQIAAMTLAYFMQTAGSDVFRKRDVVVVDEAHGLAEWAEMYATIDLKPRTVPVWDDIGVPDVAAAGDPVERASRFAEALVGVCKREKDELLTKSELTPEEAARRDRLQELIGELQWFVEDYRDPQSPTTWVVDQHDGEGSPIAIKPLDPAKYLKHTVWDRGNKFALLSATILNKAAFCRSVGLDPSKVALVDVEHTFPVENRPLYDVTQGKMTYEHRDETLPKIARLAVRLMAKHPDEKGLIHCHSYAIQAELRRRLAEMGLGNRVRGHDRDDRNVELETWKATDRPKVFLSVKMEEALDLKGDLCRWQVLCKAPYLNTNDSRVARRLEDGQWAWYRRAALRTVIQACGRVVRAPDDYGDTYVADSSLLQLFDKTRTDMPDWFAAQVDRMSEPDLPEFDPVAAGGRGGNAGDAVGGTANLGGSTSRSSGASGAGSGSRRDSTRGSGSSGSRAGGSGGASAGGSGGRKSGGSADGSDDGGRSNHPLSDVWGE
	C441_RS15220	hypothetical protein	117736	117930	MHTNALATAMTLYRSGALTLSQAAARSGYSEDDLLLALQRHGVPVHEDDAPAASLSADRPASAD
	C441_RS15225	nonsense mediated mRNA decay protein	119197	118067	MSESRDFCPRCGDPVPERPEPLPGMPRERDDVLCDSCYFEDFDLVDAPDEVQVRVCAQCGAIHRGNRWVDVGARDYTDIAIEEVSNSLGVHLNAEEVRWGVEPEQVDENNIRMHCHFSGVVRGTPLEESIVVPVSIARETCQRCGRIAGGYFASLVQVRADDRTPTTEEAETAIEIAESYIAEREEKGDRDAFISSIKRTPNGPNIKISTNKMGSGVAKQIRERFGGTIEEHPTLVTEDGDGNEVYRVTFVARLPRYTAGDVIDPEDGDGPVLVRSNRGRLKGTRLTSGDPYESEFEEGERPEAEDLGSVEDAEETTVVTVEDEHAVQVLDPETYEAKTIPRPDYFDPDAAMVPVLKSRSGLHILPEEVVDDEDEE
	C441_RS15230	phosphoribosyltransferase	119940	119302	MFADREDAGRRLADLLDEREETADLVLAIPRGGLPVGREVADRLRAPLDVVVASKVGAPDNPELAVGAVAGDGSAWWNEDLLSYLDVGDDYLDREREREAEAAREKVSLYRGGDPLPDVAEKRVVVVDDGVATGATARACLRQVVAGDAERVVLAVPVGPPHTLSELEAECDAVVAVESPEAFGAVGAFYRDFAQVSDEEAASYLRDGAGEH
	C441_RS15235	zinc metalloprotease HtpX	120065	120946	MNWKPDWGLRGRMALTMFLLFALYIVFAGVLFAYFQSLAVMAGFMGVFLFAQFFFSDKIALYSMGASVVDEDDGPQARKLHAMVGRLSQQADLPKPKVAIADTRVPNAFATGRSQKSSAVCVTTGLMDTLDDDELEGVIAHELAHVKNRDVMVMTIASFLSSIAFLIVRWGWFFGGDRDRQNMPVIVAILASLVVWIISYLLIRALSRYREYAADRGAAVITGRPSALASALLKISGRMDNVPKRDMRDTSEMNAFFIIPIKSDFIGRLFSTHPSTENRVERLRDMEREMETV
	C441_RS15240	hypothetical protein	120953	121558	MGLFDSFRAMLGISAESDATTKADPEDLFGMSTAYLTMEADLRFDSADEAALCFSSVDSTDFADTVDAVEDILTAGSEETGTEFRRHTDGHGYNWVVLADDDPEDLVTSVHFAADEFIERGYGSRLLAALFGFERDGDRAYWIYSFRRGAYYPFAPQGTSTRNQSLEFKLESVLDGELEIEDDESYWYPLWPSTPNGHPWD
	C441_RS15245	DNA repair and recombination protein RadA	121797	122828	MAEDDLESLPGVGPATADKLTDTGYDSYQSIAVASPGELSNKADIGSSTASDIINAARDAADVGGFETGSMVLERRQQIGKLSWQIDEVDELLGGGLETQSITEVYGEFGAGKSQITHQLAVNVQLPPEQGGLGGGCIFIDSEDTFRPERIDDMVRGLEDDVLEATLEDRGIEGSVDDEETMQALVDDVLDKIHVAKAFNSNHQILLAEKAKELAGEHEDTEWPVRLLCVDSLTAHFRAEYVGRGELAERQQKLNKHLHDLMRIGDLFNTGILVTNQVASNPDSYFGDPTQPIGGNILGHTSTFRIYLRKSKGDKRIVRLVDAPNLADGEAIMRVQDAGLKPE
	C441_RS15250	NAD(P)/FAD-dependent oxidoreductase	123020	124165	MTHRIVVVGGGTGGTVVSNRLAEELESEIDAGDVEVTLVSDDTKHVYKPVFLYVPFGVAEPEDGVRDLRDLVDERVNIVTNRVRRVETDEKRLYCQDGDEVLDYDTLVLATGAKLDPDAVPGFREGAHHFYSAEGAERLRDALAEFDGGRLVLSVVGTPHMCPAAPLEFTFIVDDWLREQGLREDTDLVYTYPMERSHGKPEVAEWADPILAERGVRVETDFVVDAIDPDERVVSAKSGAEVDYDLLVGIPPHRGDELIVDSGLGDAGWVDVDQRTLRATAAEDVYAIGDTAALPIPKAGSAAHFQAFAVAERIAAEVRGRTPTKRYDGKTVCFVETGLDEASFVSFDYETPATMRQPSKPIHWAKHAYNESYWLTARGML
	C441_RS15255	DUF1641 domain-containing protein	124176	124589	MQDHESTTTTEQQVPDELVRAIENNPEEVALLVERLGLVNDLIDVLELGVGALDDEMVRSLARTGTSLAEVADDASDPDTVAGMKRLLRAVGDAEDAEATPVGAVGLLRATRDPEVKAGLGYLVALAAALGAGTDAE
	C441_RS15260	SUF system NifU family Fe-S cluster assembly protein	125064	124636	MGIGSDMYRQQIMDHYKNPRNHGRLESPTFTHTGENPSCGDTITMDVQLADDGETIERVAFSGDGCAISQASASMLTQRLPGTTLSELEAMDTDDITEMLGVDISPMRIKCAVLARQVAQDGAKIHDGEIEIEQTKTEDGDD
	C441_RS15265	mechanosensitive ion channel	125724	125137	MRQSLTGFLVETLRETVAEFGAAVQDAAPKVLTAVVFLALAYVGIRALLFVVRGVLDGLYPEEQDLVVELGVAVAGVFLWFGAALALLNIVGMTEIAASLGTATGFIALGVSYALSNMIADTVAGVYLLRDPDFNPGDRVKADPVTGTVSSIELRKTRFENDEGDTVVVANRDVEKKWTKYDAPAAEDASASDAT
	C441_RS15270	cysteine desulfurase	127079	125799	MRVQESYPVDVDAIRADFPILQRKVGGDISTPGEHDDDDTPLVYLDNAATSHTPEQVVDAIVDYYHGYNSNVHRGIHHLSQEASVAYENAHDRVAEFIGASGGREEVVFTKNTTESMNLVAYAWGLDELGPGDSVVMTEMEHHASLVTWQQIAKKTGAEVRYIRVDDDGRLDMEHAKELIDDSTKMVSVVHVSNTLGTVNPVSELAEMAHEVGAYAFVDGAQSAPTRPVDVEAIDADFFAFSGHKMCGPTGIGALYGKRDILDEMQPYLYGGEMIRSVTYEDSTWEDLPWKFEAGTPPIAQGVGFAAAVDYLDDIGMENVQAHEELLAEYAYDRLSEFDDIEIYGPPGDDRGGLVAFNLDSVHAHDLSSILNEQGVAIRAGDHCTQPLHDKLGVAASTRASFYIYNTRAEIDALVDGIDAARELFA
	C441_RS15275	PAS domain-containing sensor histidine kinase	127248	128294	MSNATSSSLAFSSLDALPTQLAILDEEGVIVYTNRAWREFGNEHGYQGDSSSVGMNYLGVCDLSGATDATTASEGIRAVIDGDREAFSFEYPCETPDERLWFTMRATRFVDGGDTYVQIAHLDITDRKRAELEAEEKAERLQNLARMLSHDLRNPLSVAVGYVDSLLDEVVDADGLEQVAGALDRMDDIITDGLVLARHDTVGELSTVDLETRAATAWAHVDTGSAELVVADSFEFRADPSLLGHVFENLFRNSVEHGANDGGLTVTVGVLGGDGDATGFYVEDDGVGIAAEARDEVFEAGYTTGEEGTGLGLSIVAQAVRAHDWDVAVTEAERGGARFEITDVERPA
	C441_RS15280	DUF424 family protein	128641	128339	MLLRERETPEGLLVSVCDPDCIGETYTDDGVSLDVTEDFYGGDEAETADEDAVVDSLTRATVANIVGEESVSVAIDAGLVDEETVLEVGGTLHAQLLWLR
	C441_RS15285	tetratricopeptide repeat protein	129382	128642	MTDDGKRPHRFSEGQGFDEDYSDFSLDPPELSVDPTKVDPVDSRVLTDILDQRNIDPEDVDIEKLLDVALSYMQINRFEEATGAFERVARFAGDDDDIAQEAWVNKGAAHGQLEEWDEAIGSYQEALKLDDDSEHAATAHTNLAYALWEAGQTADALDHAERAVELDPRFPQAWYNRGFFLHERGLNEDAVNAFDNAIRLGMRTPGVHEEKARALEELGRDEEAEQAQQQADDLREQAEAELVEEY
	C441_RS15290	histidine phosphatase family protein	129474	130088	MSAPPTTVVSFVRHAHAPSVPDAERARGLSRRGRRDAARVTARLADLADVVATSPAERARATVEGVADAADAPLIVDDDLRERELAESPVEEFDEAVEHLWANPNASHPGGESHAEAQARGVAAVGRLVEAYPDRHVVVGTHGTLMALVFNAYDPRYGREFWTGLTTPDVYEVTFVDGEAFSIARTWTPEADDRADADRDPAER
	C441_RS15295	RNA 2',3'-cyclic phosphodiesterase	130115	130669	MRCFLAVDLPDSLAAGVAAVQDRLSDADGLRFTDPERAHVTLKFLGEVSPDRIAEVEDAVESAVEDAGVGPFDASVGGLGVFPSLDYIRVVWVGVGDGAAELTQLHEAIERETTALGFDPENHDFTPHVTLARMDDARGKVLVRRVVEDESSTVGSFRVREVRLKKSDLGPDGPEYETVTRFSL
	C441_RS15300	DMT family transporter	131617	130676	MSRAKTAVAFLALSAVWGSAFLATDIALRTVPPAFLGAVRFDVAALLLFAVAVARGDRVIPAVRDEWRPILAGGAFSIGAHHALLFSGQVYVPGSVASVLLGIIPLATPTLTRLTATRERLSPHRVVGLVLGFLGLVVIANPDPGNLLSSNLVGAVLVFGSAVAFALGAVLTHDSETGMSLLAVQAWMMLVGAVTLHVTSAALPWESAADAAWTQTTLVAAGYLAVVAGAGGFLLYFWLLDRVGPIEVSLLEYVIPLFAALADWTVLGRVPTRATVAGFALIFAGFLLFKRDVIRGELRRVVDRRRGRRPTDD
	C441_RS15305	50S ribosomal protein L39e	131790	131942	MGKKSKSKKKRLAKLERQNSRVPAWVMLKTDMEVTRNPKRRNWRRSNTDE
	C441_RS15310	50S ribosomal protein L31e	131946	132224	MSANDFEERVVTVPLRDVQAVPAHERAGRSMTLIREHLAKHFKVDAENVRLDTQINEDIWAHGRQSPPSKFRVRAARFDEDGESVVEAEPAE
	C441_RS15315	translation initiation factor IF-6	132228	132893	MLRASFAGSSYIGVFARATDDALLVRPDADDSLAEQMAEELDVPLVKTTVGGSGTVGALATGNENGLLVSSRATSREKEALTDAVDLPVYELPGRINAAGNVVLANDYGAYVHADLSDEAVAAVEEALEVPVERGDLADVRTVGMAAVANNRGVLCHPKSREPELEALEALLDVRADIGTINYGGPLVGSGLVANDEGYIVGEDTTGPELGRIEDALDYID
	C441_RS15320	50S ribosomal protein L18a	132975	133151	MSQFIITGSFTSRGVVHEFTKTVEAPNENVAQERAFSLIGSEHGIKRTKVELNEVSAA
	C441_RS15325	prefoldin subunit alpha	133151	133621	MGGGQQQLQQLSQELQAIDEEIESLESEVSDLNTEKNEIDEAVEAIETLETGSTVQVPLGGDAYLRAEVQDIDEIVVSLGANYAAEQEQSTAIETLRRKQDALDEEIASVRGQIEELEEESDEIEEQAMQAQQQMQQQQMQQMQQMQGEGGDGDDE
	C441_RS15330	signal recognition particle-docking protein FtsY	133648	135006	MFDGLKKKLNRFRNDVEETAEEKAEAAADEAEADADAEAESAPAGAEHAAVEPEASEPADVDSESDAVGDADAGSEADAVGDAPADAASASAAVESESDSEAAATPEPDSEVDADTDTDADAGDGPAADEAEPRESLASDAAKAALTEEDDDDSSGPGRLRRAAAFATGKVVIEEEDLEDPLWELEMALLQSDVEMQVAEEILETIREKLIGETRKQVQSTGQLVSEALHDALYEVISVGQFDFDQRIAEADKPVTLIFTGINGVGKTTTIAKLARYFEKQGYSTVLANGDTYRAGANEQIREHAEALGKKLIAHEQGGDPAAVIYDGVEYAEAHDIDIVLGDTAGRLHTSNDLMAQLEKIDRVVGPDLTLFVDEAVAGQDAVERARQFNDAAAIDGAILTKADADSNGGAAISIAYVTGKPILFLGVGQGYDHIEKFDPEQMVNRLLGEDE
	C441_RS15335	LysE family translocator	135659	135042	MTTLAFGLDVATYLAFCGAAVALILAPGPDTMYVLARGLDGRGPGVRSAFGIATGVLFHTLLATVGAAALFRAVPEAAAALKYVGAAYLGYLGVAALRNDEFDPAVETERGASFRRGVLVNALNPKVALFFLAFLPGFAGQGAGSGVRMASLGATYAALTALYLSVVALGADRLGARLAETRVASALNYVGAGTMLLLGVVLVLE
	C441_RS15340	D-2-hydroxyacid dehydrogenase	136667	135693	MTTILVLDRPTHGIPASEYAAALRERLPDATVRHPKTSAETLDAARDATVITGTSLPDDVLDAADELRLFAGATAGYDHLPLEALRERGVVVTNASGVHGPNIAEHVLGWLLMITRRLDEGLRRQRRREWRRFQSYGELQGSTATVVGLGAIGRAVVERLDAFGVETVGVRYTPEKGGPTDEVLGFDDLEPALVRTDFLVVACPLTDETRGLIDSRALEALPTHAVLVNVARGGVVDTDALVSNLRDNRLRAAALDVTEPEPLPEDHPLWGFENVYITPHVSGHTPHYWTRVADILAENVERLAAEPEDETPALRNQVVPSPNP
	C441_RS15345	signal recognition particle protein	136758	138152	MVLDNLGSSLRGSLDKLRGKSRLDEDDVQEIVKEIQRSLLSADVDVSLVMDLSDSIKTRALEEEPPGGTNARDHVLKIVYEELVDLIGESTEIPLESQTIMLAGLQGSGKTTTSAKMAWWFSKKGLRPAVIQTDTFRPGAYDQAKQMCERAEVDFYGDPDCDDPVQIAREGLEATEDADVHIVDTAGRHALEDDLIDEIEEIEGVVQPDLNLLVLDAAIGQGAKEQAQQFDESIGIGGVVITKLDGTAKGGGALTAVNETDSSIAFLGMGETVQDIERFEPNGFISRLLGMGDLKQLSERVERAMSETQAEDEDWDPEEMMKGNFTLKDMQKQMEAMDKMGPLDQVLDMIPGFGGGIKDQLPDDAMDVTKDRMRAFEVIMDSMTEAELENPRKVGASRVKRIAQGSGQDEETIQELLEQHRMMEQTIKQFQNMGDGDMQRMMKKLQNQGGGGGGMGGLGGMGPF
	C441_RS15350	divalent cation transporter domain-containing protein	138254	138835	MTVRDVAVEAYKEALPALAASLVGGLIAGVVLGGMRAELRAVPGLLVLVPALLATRGNVYGSLGARIATALHQGLIEPRVTGGDERLRAAATAALANGVLTSTFAAVVAFFLLTFLGSRVAPLPILVGVAIVAGLLSGIVLTVVVVSVVFAGYRRGRNPDTIVGPVVTTTGDVFGVLFLLIAVRTVLAVAGVF
	C441_RS15355	divalent cation transporter	138836	139396	MPTEWTVRAITRAMLPVLLVLTLVELGSGLVLGSFEAQLLRYPSLLVLVPVTIGTAGNLGSVLAARLSTSFHLGTLSFSPRDDELAGNAVATVALAVTVFPVIGAGAWVATLLVSGDTSLALQKVVLIALSSGISLAVLAVAVTFSATYVAYRFGLDPDDVVIPVVTNVCDVLGVVVLFGVAQVLV
	C441_RS15360	hypothetical protein	139474	140523	MQSSAVLPVLFEVLPRVARIAAYIAVGVFAANLVVAFGLVERIAGLSRYLTSPANLPDEVGTAIVTTAASTTAGYGMLAEFRESGVLDDRATLVAVTINTFFGFVQHIFTFYWPVLIPILGREVGFMYVGARAAIALAITATGVVAGAVLLSDRNTTPVAVAETDGSGGAVDAAAADGAGGGDAADSSDAADSSDAADTDDTLRETVEDAARSTWDKLRRIVPRLAVVYVAVTLLLRTTDLESFAALASPLTNLVGLPGAAVPVVVAFAFDTTTGAATIAPAVGETFTPKQAVATMLIGGIISFAVSTFKRSIPFQYGIWGPEFGSKVIAVNTGLKIVFIGVAVALLVA
	C441_RS15365	hypothetical protein	140982	140566	MIYSVDVRIEVPVRDTEVTDRVGDAVENIFPGVELDHEPGKLVGETHELERFSERLHEQAILDTARREFAKRRDDDGFSFALKKQAAFKGVVNFSVGNPDELGDIDVHVTVRDPSVDEVIDYIAPPTEDGRPVDPNGR
	C441_RS15370	flagellar hook-basal body complex protein FliE	141554	140985	MRVIGTVGLPGSGKGELAEVARNAGVPVVTMGDVIREECRERGLDPATDHGKIATALREEEGDDAIAARSLPMVEDLLESNDVVVVDGLRSGVELDRFREAFGDDFVLVSVEAPFETRAERLLDRDRDDSDTDVEALKKRERRELDFGMGDAMDRADVVIQNTGTLAEYRETITRLFEEGPEALAEADA
	C441_RS15375	hypothetical protein	141683	142060	MSQRSFVVRALWFVFVGWWATPAVVNVAWFLNATVIGIPLGVALINLVPTVLSLKEPKTRLDPDSGRGQRSLVVRAVYFVFVGWWLSWLWANVAVLFTLTIIGLPVGIWMLNRLPAVTSLYRFDG

view raw out.tsv hosted with ❤ by GitHub

[fhsantanna]

Thank you very much. But for 100,000 files this is not feasible.

[Pierre Lindenbaum]

But for 100,000 files this is not feasible.

a loop ?

[fhsantanna]

Sorry, you are right. I did not pay attention. Maybe your solution is faster than mine. I'll test it. Thank you again.

[fhsantanna]

Could you provide your awk code, please?

[Pierre Lindenbaum]

something like (not tested):

awk -v B=123  -v E=456 '{x1=int($2);x2=int($3);b=x1<x2?x1:x2;e=x1<x2?x2:x1; if (!(b>int(E) || e<int(B))) print; }' input.tsv