Entering edit mode
9.5 years ago
correia.mirandacristina
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10
I am looking at Structural Variant analysis with WES data. Is qSV compatible with WES or just WGS? Any other suggestions? Thanks
Cristina
Structural variants cannot be captured in exome sequencing? Any alternate methods?
To some degree they can be, as Ying pointed out you may be able to capture some within-gene duplications, deletions, etc. through breakpoint analysis. Those are relatively rare though, and you'd be much more likely to find structural variation within whole genome sequencing data. This is particularly true with larger scale structural variation that may span multiple genes.