Prottest output to Raxml input
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5.4 years ago
yp19 ▴ 70

Hi all!

I ran Prottest to determine the best model for a given protein sequence alignment, so I can eventually use that model in RAxML. The output of Prottest tells me that the best model according to AIC is: WAG+I+G+F.

Now I have to set the model in RAxML command. Based on the RAxML manual I think "WAG" is the model, "I" is for invariant sites, "F" is for using empirical AA frequency, but i'm not sure what the "G" is for? This is what I have come up with, does anyone know if this is the right model based on the Prottest output?

raxmlHPC-PTHREADS-SSE3 -m PROTGAMMAIWAGF

Thanks!

prottest raxml • 1.9k views
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5.4 years ago
flogin ▴ 280

G represents a Gamma Distribution (see http://treethinkers.org/tutorials/the-gamma-distribution/ for a well detailed explanation).

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5.4 years ago
Mensur Dlakic ★ 28k

Your command correctly interprets the prottest output.

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