How to efficiently fetch methylation beta values across multiple genes for multiple samples?
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5.3 years ago
n,n ▴ 370

I wish to obtain the methylation beta values across all genes from normal tissue (colon, blood, etc.) samples in a text file of some sort. I've never worked with expression/methylation data before and I'm unsure on how to do this efficiently. So far I've looked into this database: http://mgrc.kribb.re.kr:8080/MENT/#main

The latter contains the data I want and its very neatly organized; however, you can only download the values for only 1 gene at a time making it impossible to obtain all the data I want in a reasonable amount of time. Ideally I would like to fetch the values for all genes from each individual sample.

I've also tried looking into the GEO database as I understand this is the go to source when trying to fetch large amounts of methylation/expression data, but I can't seem to make any sense of the files deposited in GEO as I never worked with them before. Any help would be greatly appreciated.

mehtylation database • 790 views
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