UK Biobank reference genome?

Question

[Sal.Leggio63]

How do I find out the reference genome for the UK Biobank? If you could direct me to an article that I could cite, that would be terrific.

Answer 1

[Kevin Blighe]

I searched the official docs and found GRCh37 (hg19). Take a look:

• http://www.ukbiobank.ac.uk/wp-content/uploads/2017/07/ukb_genetic_file_description.txt (from THIS page).

Answer 2

[Eric T.]

The exomes are aligned to GRCh38 with the "chr" prefix removed from the sequence names.

The older SNP array genotypes, as Kevin noted, use GRCh37 as the reference.