Figure Explaining What Is A Snp

Question

[1234Jc4321]

Could anyone suggest me a nice picture showing properly what is a SNP. I have to explain this concept to people unfamiliar with genetics.

thx

Answer 1

[Jeremy Leipzig]

[Casey Bergman]

I think the figure is trying to show the SNP is not associated with bad taste in trousers

[brentp]

I agree with Jan, that it might be better if there was a group of people with G and another with C

[Larry_Parnell]

Very self-explanatory. I'd present this figure first, then get more serious with the APOE example.

[Jeremy Leipzig]

i didn't draw this so i'm not sure what the deal is with the pants

[Jan Kosinski]

Isn't that figure showing mutation instead of SNP? I always thought SNP implies some allele frequencies like for "genetic polymorphism" http://en.wikipedia.org/wiki/Polymorphism_%28biology%29#Genetic_polymorphism

[brentp]

and yes, it'd be nice if one group had a higher frequency of ugly "trousers".

Answer 2

[Larry_Parnell]

I would show an alignment of the portion of the human APOE gene showing the epsilon 2, epsilon3 and epsilon 4 alleles: E2 = rs429358 T and rs7412 T; E3 = rs429358 T and rs7412 C; E4 = rs429358 C and rs7412 C. Many people know this disease and many are interested or afraid to be tested at these SNPs.