DMRcate results: How to interpret the overlapping.promoters

Question

[sugus]

Hi there,

I am using CHAMP to perform differential methylation analysis, including DMP and DMR. Regarding DMR, I used DMRcate algorithm and I am a little bit confused about the result.

In the derived table of DMRcate embedded in CHAMP, I got a column of overlapping.promoters. For example:

                        seqnames    start      end width strand no.cpgs        minfdr      Stouffer  maxbetafc meanbetafc
chr20:61049813-61051915    chr20 61049813 61051915  2103      *      27  0.000000e+00  0.000000e+00  0.4770680 0.35455081
chr20:57424521-57431303    chr20 57424521 57431303  6783      *      77  0.000000e+00 2.725637e-268 -0.2084268 0.07728631
chr20:24448859-24452131    chr20 24448859 24452131  3273      *      21  0.000000e+00 1.434465e-236  0.4263522 0.28291317
chr20:21491781-21498921    chr20 21491781 21498921  7141      *      26 3.342271e-208 4.594347e-231  0.4385002 0.25698803
chr20:61806628-61810795    chr20 61806628 61810795  4168      *      23  0.000000e+00 8.953525e-215  0.4182034 0.24114120
chr20:37351945-37358077    chr20 37351945 37358077  6133      *      23 1.003282e-251 2.186334e-208  0.3632555 0.20988842
                                                                                                                       overlapping.promoters
chr20:61049813-61051915                                                                                         GATA5-001, RP13-379O24.3-001
chr20:57424521-57431303 GNAS-050, GNAS-037, GNAS-058, GNAS-001, GNAS-009, GNAS-049, GNAS-AS1-001, GNAS-036, GNAS-059, GNAS-012, GNAS-AS1-004
chr20:24448859-24452131                                                                                                          SYNDIG1-001
chr20:21491781-21498921                                                                                           NKX2-2-001, NKX2-2-AS1-001
chr20:61806628-61810795                                                                                       MIR124-3-201, RP5-963E22.4-001
chr20:37351945-37358077                                                                                                          SLC32A1-001

And what confusing me is why there is a number coming after each gene, like GATA5-001, what is that supposed to mean? And how can I select the significant DMR, just refer to mindfr or stouffer? What about the threshold? I didn't see the threshold in its R help document.

Hope someone could give me a hint! Many thanks advanced.

[AR]

Did you find an answer to this? I had the same question.

Thanks.