We have identified a set of genes to be differentially expressed between treatment and control. The current gene annotation doesnt have functional information about the gene.
What we would like to do is asses the biological functions of these genes( may be based on GO and then cluster them). I was wondering if there is something already out there to do so in semi automated way.
I am thinking of blasting them against pfam or be myhits dbase but wanted to take your opinion.
PS : cross posted on BioConductor mailing list
Thanks! -Abhi
The approach you take and the usefulness of BLAST, GO, or other tools in relation to even other datasets to which you can compare depends on which organism you're studying.
What are the IDs for your genes? Are they Entrez Gene IDs, unigene, or what?