Modular differential connectivity

Question

[anand.gururajan]

Hi.

Using RNA-seq data, i've managed to generate modules using WGCNA that are unique to specific experimental groups. This was using the tutorial on the UCLA website.

I'm now trying to look at connectivity within a module. I have access to the R script (https://www.rdocumentation.org/packages/DGCA/versions/1.0.1/topics/moduleDC) but am wondering if there's a good tutorial using a sample data set on how it should be used?

Thanks everyone.

Answer 1

[Kevin Blighe]

Not sure about tutorials for this specific topic but you could look at a previous work, also by Horvath (WGCNA co-developer), where they performed some differential analysis:

• Data and Statistical R Code: Differential Network Analysis

Kevin

[1769mkc]

this is what i been looking for when I search "module differential connectivity " i get this library "DGCA" .Its bit confusing if it can be done using WGCNA only or the DGCA library .