alignment tool for big data

Question

[gbahramali]

Length of my sequence is 7000000bp and I want to align with other sequences which tools are good for this

[Joe]

The 'answer' to this is you don't align sequences of that size, certainly not for multiple sequence alignment and phylogenetics.

You need to use an indirect approach such as aligning orthologues, or computing a mash tree.

[gbahramali]

I want to drow phylogenetics after multiple sequence alignment

[GenoMax]

Please use ADD COMMENT/ADD REPLY when responding to existing posts to keep threads logically organized. SUBMIT ANSWER is for new answers to original question.

[gb]

same question: how many genomes from BLAST hit should be considered for phylogeny tree analysis?

(Open the link, the title does not describe the question very well)