How to calculate N in TWAS simulated data

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5.1 years ago

printingdots • 0

I am new to this area and I went through some tutorials and software on how to simulate and format my own TWAS data. However, I noticed that most software do not produce the N column in the output. I understand how we are getting CHR, BP, SNPs, allele columns and Z/p-score statistics. Please can someone explain how we get different values of N for different SNPs?

Edit: I should mention that I'm trying to generate TWAS based on .bim/.fam/.bed files

twas • 908 views

ADD COMMENT • link updated 5.0 years ago by Biostar 20 • written 5.1 years ago by printingdots • 0

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What do you mean by N ?

ADD REPLY • link 5.1 years ago by GouthamAtla 12k

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Number of samples of each SNP

ADD REPLY • link 5.1 years ago by printingdots • 0

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Are you talking about Transcriptome Wide Association Studies ? What softwares are you talking about ? No. of samples for each SNP ? Or the sample size required to perform TWAS ?

ADD REPLY • link 5.1 years ago by GouthamAtla 12k

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Resolved. It was number of samples for TWAS.

ADD REPLY • link 5.1 years ago by printingdots • 0

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