Variants effect predict

Question

[yehchan57]

Now I have some mutation information on some sites in vcf format? How can I predict if these mutation result in loss of function or gain of function?

[WouterDeCoster]

You tagged VEP and annovar in your question. With those you can annotate variants in vcf format. What is unclear after you have read the documentation of these tools and used these on your vcf?

[Mark]

Use software that annotates variants: tools for variant annotations