Question

Finding of essential genes using database

0

Entering edit mode

5.0 years ago

anis.geb.cu ▴ 30

Hello! I have a dataset of 1092 human non-homologous proteins of Streptococcus pyogenes MGAS5005 (those are selected after following different subtraction processes) of which I want to find out the essential genes. Previously I have done this job using BLAST (with my dataset) against Database of essential genes (DEG). But DEG server is currently down and I badly need to do this job. Can anyone help me with any alternative option or simply how this work can be done without DEG?

Essential genes DEG BLAST • 965 views

ADD COMMENT • link updated 5.0 years ago by julien.fouret.fr ▴ 20 • written 5.0 years ago by anis.geb.cu ▴ 30

1

Entering edit mode

Are you using the new version of the website at http://www.essentialgene.org/? Seems to be working for me.

ADD REPLY • link 5.0 years ago by i.sudbery 20k

score 1 · Answer 1 · 2019-12-08

Hi,

Are you using this link : http://tubic.org/deg_bak/ ?

It seems that this database has moved here : http://www.essentialgene.org/

The following message appears on their website,

The new release is still under test. The old version is at: http://tubic.org/deg_bak/ The Genome-BLAST searches against DEG are available now. If you have any problems, please send email to Hao Luo.