Interpreting a p-value from a fisher exact test?
1
0
Entering edit mode
5.0 years ago
a4appy23 ▴ 50

I did an fisher exact test to investigate if DE genes are significantly overrepresented in terms of diabetes genes.

I got an p value of 0.83. other than accepting and rejecting the null hypothesis based on cut off value 0.05 how do i interpret it?. i mean what does the p-value of 0.83 mean here?

the count table is attached below. where diabetes_t means true and diabetes_f means false on the table.

https://imggmi.com/full/2019/12/9/f5d85ed10052e808d3aa981a25773a6f-full.png.html

RNA-Seq rna-seq genome gene R • 928 views
ADD COMMENT
4
Entering edit mode
5.0 years ago
Ahill ★ 2.0k

Assuming single-tailed test, under the null hypothesis that there is no enrichment of diabetes genes among your DE genes, the probability of a 2x2 table as extreme as yours is high (0.83). This indicates no strong evidence of an association between a gene being DE in your experiment and also being a diabetes gene.

ADD COMMENT

Login before adding your answer.

Traffic: 2025 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6