How to make design and contrast matrix for microarray analysis using EventPointer?

Question

[deepak18]

I am new to analysis of microarray data using R. I am using EventPointer package to analyze HTA 2.0 array data. Can someone elaborate on the design and contrast matrices that are required for this package to function? (https://bioconductor.org/packages/release/bioc/vignettes/EventPointer/inst/doc/EventPointer.html) Thanks in advance.