Convolution and deconvolution in gene expression

Question

[premraj.preeti]

Hi All,

I am trying to understand the mathematical concept behind convolution and deconvolution in gene expression. Went through various papers but they are way too complicated. Can anyone provide simple mathematical explanation.

Thanks for your help in advance.

Answer 1

[Gjain]

This is a good paper to go through

Wang, X., Park, J., Susztak, K., Zhang, N. R., & Li, M. (2019). Bulk tissue cell type deconvolution with multi-subject single-cell expression reference. Nature communications, 10(1), 1-9.

Link: https://www.nature.com/articles/s41467-018-08023-x