My colleague and I are holding different opinions about positive selection. The major issue is whether positive selection can be done among multiple copies of a gene within the same species. I think it can. But I cannot find suitable cases to prove it. The papers I have got mainly deal with positive selection among species. Some papers conducted positive selection within species. However, they used cDNA information and SNP from multiple species. For example, Moy etal. (2008) analyzed intraspecific diversity in oyster sperm bindin. Ramensky etal. (2008) found that alternatively spliced exons of human genes were under positive selection. I wonder whether there is an example that analyzed the multiple copies of a certain gene within the same genome (without using multiple individuals) and found the genomic copies were under positive selection. Do you know such examples? If any, please share with me. I will continue to search for such examples, and will share it with you if any. Thanks!
Hi, I am back with two examples. Both are from MBE. (1) Large Gene Family Expansions and Adaptive Evolution for Odorant and Gustatory Receptors in the Pea Aphid, Acyrthosiphon pisum (2)Positive Selection and Expression Divergence Following Gene Duplication in the Sunflower CYCLOIDEA Gene Family