Forum:Develop New Algorithm For Matching Dna Sequence
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13.6 years ago
Nimka ▴ 20

Hi, I am a student and I am doing my final year project on bioinformatics. I want to develop a new algorithm for matching DNA sequence from DNA database. Please can anyone help me from where I can start this project? I searched a lot on previous algorithms like Smith-Waterman, BLAST and FASTA but I am still confused about my project what should be first step and then second. And so on and then final step...

dna sequence • 3.3k views
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Hello, I am also a student doing my final year project on bioinformatics. I don't know if this will help, but I can tell you what I am doing. My professor gave me a list of pairs of protein names. Using Biopython and E-utilities, I retrieved the sequences of the proteins and put them into local files. My next step is to implement a Smith-Waterman program. Then I will compare these results to other implementations already in existence. One in mumps that a professor wrote, BFast, exonerate: http://www.ebi.ac.uk/~guy/exonerate/index.html http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0007767 Maybe some others, and try to improve mine? I think compare them for speed. I would be interested to know how your project turns out- and if you develop a new algorithm. Best of Luck! Laura flitrfli at gmail dot com

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