Help for a perl script.

Question

[Anisur Rahman]

I found a perl script related to siRNA design. And, I am planning to use it for one of my projects. But the script is written to use in the windows operating system. The overall installation instruction is quite complex and some of the required softwares are outdated. I think using this script in linux directly will be easier. So, I have to make this script compatible with linux system. But, my knowledge of perl is not enough to make the changes. Will any of you please help me? . You will find the script in the supplementary material section from the following link: MysiRNA designer-PlosOne

[ATpoint]

But, my knowledge of perl is not enough to make the changes.

Well that is a problem. I doubt someone will really be open to do your work. There are plenty of these prediction tools, why not just using a different one that is working on your system?

[Anisur Rahman]

My bad luck!! Actually I'm especially interested in this script because it automates the overall process. Thank you!

[ATpoint]

There are many tools that can do this job. Don't waste your time on this one. browse the literature for alternatives, I am sure you'll find a satisfying alterative. By the way, based on the experiences our lab made with these sh/siRNAs you should always try published ones first. You will have it often that they simply do not work in the cell so try validated ones first. Still, no guarantee this will work in your cells but it is a good starting point.