Whole human genome sequence of COVID19 patient
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4.6 years ago

I am looking for a whole human genome sequence of COVID19 patient. Is there anything published? Thanks in advance.

covid19 • 1.4k views
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I am not aware of such a genome. Why do you think that would be useful?

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Has been mooted that there may be 'protective' variants.

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Then you would want genome(s) of a person(s) who has recovered from or never got COVID in first place.

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Semantic argument, but let's not pretend that isn't of interest to bioinformaticians!

Protective means reducing an effect including mitigating entirely.

You'd want genomes, definitely plural, from a large cohort of patients, definitely that had tested positive for Covid-19, that had a well quantified phenotype of severity of disease.

I think it's a bit of reach, although colleagues are going to do this and I will be analysing it...

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Completely agree about your thought!!

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Agree. A comparison of recovered patient and not- recovered (death) patient, could be an interesting point to study.

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User "genomax" has one of the clear thought of application.

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I am not sure if people are sequencing the genome of the affected/recovered patient or not. But hopefully, genome comparision will give us some interesting insight. Waiting for the public data !!

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Don't count on it. It's not sufficiently relevant to justify spending thousands on sequencing these genomes while I can already tell you old age and comorbidities will get you killed.

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4.6 years ago

That seems unlikely. What might be feasible is to find the genome of a cell culture line bring used in research.

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