Is indexing a genome the same as annotating a genome?

Question

[ATCG]

Is indexing a genome the same thing as creating annotations?

For example, in Samtools we use the index option with a genome.fasta and transcripts.fasta and the output is a bam file does this file contain annotations? If so, is this bam file similar to a .gtf or .gff file?

Thanks!

[ATpoint]

what is the purpose of indexing a genome

Answer 1

[GenoMax]

No. Indexing is a procedure used to facilitate fast random access in sequence/index files.

Genome annotation on other hand is a process where we identify location of coding exons, introns and other genomic features, which leads to creation of gene models that then get encoded in GTF/GFF files.

BAM files do not contain annotations.