Polymorphism of protein location on chromosome in VCF file

Question

[kedic715]

Using VCF file or gnomAD browser, how can I find which position of a protein has polymorphism? If using python, will pyvcf library be useful and how to use it efficiently? Solutions on R will also be helpful! Thank you so much in advance.

Answer 1

[JC]

Use Ensembl VEP to annotate your VCF and the impact in proteins