Validation of protein-coding gene and lncRNA correlation

Question

[seta]

Dear all,

I obtained several correlations (based on Spearman test) between some differentially expressed protein-coding genes and long non-coding RNA (lncRNAs) obtained from a RNA-seq analysis (human). However, I would like to further validate these observed correlations using in silico analysis, not experimental methods. Could you please share your idea about this issue?

Many thanks

Answer 1

[caggtaagtat]

Maybe the WGCNA R package could be of interest here.

[seta]

Thanks. As far as I know, this package also works based on the correlation. Any other suggestions?