Phasing non-human genomes with Beagle - do I need to divide subjects by population?

Question

[mstagliamonte]

Hello, BioStars Users,

As per title, I intend to phase my samples using Beagle, either v 4 or v 5. I also have recombination data available from literature. I was wondering if I need to split my input file dividing the subjects by population. I currently have a total of 150 subjects, what minimum sample size would I need for reliable results?

Thank you for your kind attention,

Max

[Jautis]

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