Ribo-seq data analysis using an RNA-Seq analysis pipeline

Question

[ATCG]

Hi, Anyone familiar with Ribo-Seq analysis, Is it possible to apply an RNA-Seq pipeline to Ribo-Seq and TRAP-Seq data? Thanks!

Answer 1

[Kristoffer Vitting-Seerup]

I'm not an expert in Ribo-seq but I don't think you can directly use an RNASeq pipeline as there are many QC steps you want to consider when handling Ribo-seq data (codon frequency etc). Have you looked at some ribo-seq pipelines?