COG analysis using whole genome data

Question

[hafiz.talhamalik]

I want to perform COG analysis on my whole genome data. NCBI's database is there but I m not getting an idea how to use that. Is there any tool to perform this analysis?or if someone could help me how to use NCBI's COG database ?

[Mark]

The cog database, to my knowledge, has not been updated in a long long time (since 2014). If your organise is not part of the 2014 update, then you will need to manually assign cog categories to the genes. Prokka does this for you in an automated fashion.

I personally find ontology analysis (including GO terms) a waste of time. Not much is gleamed from the analysis apart from broad stroke information.

It's a good idea to post what your question is and how you think the COG database can help you answer it.