Hi, this may be the silly question, and please understand.
I'd like to know the SNPs related to personalities influencing on a specific disease.
such as:
rs3814424 (conscientiousness)
rs57590327 (extraversion)
rs2164273 (extraversion)
rs6481128 (extraversion)
(https://www.snpedia.com/index.php/Personality)
I got a bim file from MAP and PED files.
Through the data, I have the matching SNPs.
For example,
df = pd.DataFrame({'CHR': [10, 8, 3], 'RS_ID': ['rs3814424', 'rs57590327', 'rs2164273'],
'MORGAN':[1, 1, 1], 'BP_Position': [20466206, 58220209, 8262926],
'allele A' : ['C', 'C', 'T'], 'allele B': ['T', 'A', 'C']},
columns = ['CHR', 'RS_ID', 'MORGAN', 'BP_Position', 'allele A', 'allele B'])
df
I think I have to get the individuals(samples) information from a MAP file,
especially matching the above SNPs.
How can I get the information?
Do I have to use plink? please let me know the method.
Thank you.
Does SNPedia offer data downloads or APIs for query? If so, this is a straightforward task. I can't wrap my head around that website.