Finding gene ontology terms for a list of genes
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4.3 years ago
evelyn ▴ 230

Hello,

I have done a gene enrichment analysis for a list of 2000 genes using PANTHER where 300 genes were not mapped. I have got 825 Gene Ontology terms for mapped genes. Result looks like:

Category ID Mapped IDs
GO:00064 EnsemblGenome=cg0879|EnsemblGenome=cg08248|EnsemblGenome=cg07778|EnsemblGenome=cg00577|EnsemblGenome=cg01332|

where each GO term represents several genes for them. However, I want result in vice-versa form which might looks like:

Gene      GO terms 
cg0879    GO:00064  GO:00078  GO:00089  GO:00101

Is there a way in PANTHER to get result in a form I want. Thank you for your help!

gene • 1.1k views
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You can try out this perl one liner. It splits the second field by | then again by = to get the gene name, then appends the GO to each with a tab. In the end prints gene with GO categories.

perl -lane 'BEGIN{%store}{my %store=map {$store{[split /=/,$_]->[-1]}.="\t".$F[0]} (split /\|/,$F[1]); }END{foreach(keys %store){print $_,join("\t",$store{$_}) }}' test.tsv

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