protein database peptide identification

Question

[mdfardin374]

Hello all, I have a list of peptides from MS/MS analysis and I want to compare it with a known protein database to find novel peptides. Can somebody help me with some script or whatsoever? Thank you

Answer 1

[Jean-Karim Heriche]

There are two options:
- Map your peptides to a reference proteome
- Search a database of previously reported peptides (e.g. PRIDE, maybe try its peptidome)